OBJECTIVE: To analyze information on assisted reproductive technologies (ART) performed globally. DESIGN: Data on access, efficacy, and safety of ART were collected for the year 2003 from 54 countries. SETTING: National and regional ART registries globally. PATIENT(S): Patients undergoing ART globally. INTERVENTION(S): Collection and analysis of international ART registry data. MAIN OUTCOME MEASURE(S): Number of cycles performed in reporting countries and regions globally for different ART procedures with resulting pregnancy, live birth and multiple birth rates. RESULT(S): A total of 433,427 initiated cycles reported in this registry resulted in 173,424 babies born. This corresponded to a delivery rate per aspiration of 22.4% for in vitro fertilization (IVF), 23.3% for intracytoplasmic sperm injection (ICSI), and a delivery rate per transfer of 17.1% for frozen embryo transfer. Although there is wide variation among countries and regions, the overall proportion of deliveries with twins and triplets from IVF and ICSI was 24.8% and 2.0%, respectively. There were wide variations in access, and compared with the previous report (year 2002), there was a 3.9% increase in the number of reported cycles and a minor increase in the delivery rate per aspiration. There was also a marginal decline in the mean number of embryos transferred and in the rate of multiple births. CONCLUSION(S): ART access, efficacy, and safety varies greatly globally. Collection and analysis of data over time will benefit ART patients, providers, and policy makers.
OBJECTIVE: To analyze information on assisted reproductive technologies (ART) performed globally. DESIGN: Data on access, efficacy, and safety of ART were collected for the year 2003 from 54 countries. SETTING: National and regional ART registries globally. PATIENT(S): Patients undergoing ART globally. INTERVENTION(S): Collection and analysis of international ART registry data. MAIN OUTCOME MEASURE(S): Number of cycles performed in reporting countries and regions globally for different ART procedures with resulting pregnancy, live birth and multiple birth rates. RESULT(S): A total of 433,427 initiated cycles reported in this registry resulted in 173,424 babies born. This corresponded to a delivery rate per aspiration of 22.4% for in vitro fertilization (IVF), 23.3% for intracytoplasmic sperm injection (ICSI), and a delivery rate per transfer of 17.1% for frozen embryo transfer. Although there is wide variation among countries and regions, the overall proportion of deliveries with twins and triplets from IVF and ICSI was 24.8% and 2.0%, respectively. There were wide variations in access, and compared with the previous report (year 2002), there was a 3.9% increase in the number of reported cycles and a minor increase in the delivery rate per aspiration. There was also a marginal decline in the mean number of embryos transferred and in the rate of multiple births. CONCLUSION(S): ART access, efficacy, and safety varies greatly globally. Collection and analysis of data over time will benefit ART patients, providers, and policy makers.
Authors: Barbara Luke; Morton B Brown; Ethan Wantman; Avi Lederman; William Gibbons; Glenn L Schattman; Rogerio A Lobo; Richard E Leach; Judy E Stern Journal: N Engl J Med Date: 2012-06-28 Impact factor: 91.245
Authors: Eric Manheimer; Daniëlle van der Windt; Ke Cheng; Kristen Stafford; Jianping Liu; Jayne Tierney; Lixing Lao; Brian M Berman; Patricia Langenberg; Lex M Bouter Journal: Hum Reprod Update Date: 2013-06-27 Impact factor: 15.610