BACKGROUND: Early risk stratification of patients with acute heart failure syndrome (AHFS) can guide the decision to admit the patient to hospital and the choice of therapy. METHODS: Standard review methodology using Medline and Google scholar from the years 2006-present. Papers before 2006 were reviewed when necessary. RESULTS: Biomarkers used in AHFS are broadly classified based on their mechanism of action: inflammation, renal stress, extracellular matrix remodeling, oxidative stress, cardiac myocyte stress, and neurohormonal regulation. CONCLUSION: This paper provides a review for clinicians and medical scientists highlighting the most recent advances in biomarkers with application in AHFS.
BACKGROUND: Early risk stratification of patients with acute heart failure syndrome (AHFS) can guide the decision to admit the patient to hospital and the choice of therapy. METHODS: Standard review methodology using Medline and Google scholar from the years 2006-present. Papers before 2006 were reviewed when necessary. RESULTS: Biomarkers used in AHFS are broadly classified based on their mechanism of action: inflammation, renal stress, extracellular matrix remodeling, oxidative stress, cardiac myocyte stress, and neurohormonal regulation. CONCLUSION: This paper provides a review for clinicians and medical scientists highlighting the most recent advances in biomarkers with application in AHFS.
Authors: Pasqualina L Santaguida; Andrew C Don-Wauchope; Mark Oremus; Robert McKelvie; Usman Ali; Stephen A Hill; Cynthia Balion; Ronald A Booth; Judy A Brown; Amy Bustamam; Nazmul Sohel; Parminder Raina Journal: Heart Fail Rev Date: 2014-08 Impact factor: 4.214
Authors: Pasqualina L Santaguida; Andrew C Don-Wauchope; Usman Ali; Mark Oremus; Judy A Brown; Amy Bustamam; Stephen A Hill; Ronald A Booth; Nazmul Sohel; Robert McKelvie; Cynthia Balion; Parminder Raina Journal: Heart Fail Rev Date: 2014-08 Impact factor: 4.214