Literature DB >> 21533292

Advances in the treatment of keloids.

Martha H Viera1, Caroline V Caperton, Brian Berman.   

Abstract

Occurring with higher proportions in skin of color, keloid formation is seen in individuals of all races, with the lowest incidence in albinos. Interestingly, prevalence of keloids is correlated to skin pigmentation, with dark-skinned individuals suffering disproportionately. Many factors are taken into consideration when deciding which modalities to use in the treatment of keloids, including size, anatomical site, cause, symptoms, duration of treatment and not least importantly, pigmentation of the patient. In patients with skin of darker color it is necessary to communicate the effects these treatments may have on epidermal pigmentation to the patient. Of course, the best treatment for keloids remains prevention. Physicians should be alert to delays in wound healing, persistent erythema, or pruritus as impending symptoms of possible keloid formation and make all reasonable attempts to reduce inflammation and tension on the skin with appropriate methods.

Entities:  

Mesh:

Year:  2011        PMID: 21533292

Source DB:  PubMed          Journal:  J Drugs Dermatol        ISSN: 1545-9616            Impact factor:   2.114


  13 in total

1.  Cellular senescence as a possible mechanism for halting progression of keloid lesions.

Authors:  Shohreh Varmeh; Ainara Egia; Duncan McGrouther; Steven R Tahan; Ardeshir Bayat; Pier Paolo Pandolfi
Journal:  Genes Cancer       Date:  2011-11

Review 2.  Up-to-date approach to manage keloids and hypertrophic scars: a useful guide.

Authors:  Anna I Arno; Gerd G Gauglitz; Juan P Barret; Marc G Jeschke
Journal:  Burns       Date:  2014-04-24       Impact factor: 2.744

3.  Giant keloid of left buttock treated with post-excisional radiotherapy.

Authors:  Michele Troiano; Anna Simeone; Gerardo Scaramuzzi; Salvatore Parisi; Giuseppe Guglielmi
Journal:  J Radiol Case Rep       Date:  2011-09-01

Review 4.  Keloids: Current and emerging therapies.

Authors:  Nkemcho Ojeh; Ambadasu Bharatha; Uma Gaur; Andrew LeRoy Forde
Journal:  Scars Burn Heal       Date:  2020-08-10

5.  Asiatic acid isolated from Centella asiatica inhibits TGF-β1-induced collagen expression in human keloid fibroblasts via PPAR-γ activation.

Authors:  Difei Bian; Jizhou Zhang; Xin Wu; Yannong Dou; Yan Yang; Qian Tan; Yufeng Xia; Zhunan Gong; Yue Dai
Journal:  Int J Biol Sci       Date:  2013-10-25       Impact factor: 6.580

6.  Keloid Management: A Retrospective Case Review on a New Approach Using Surgical Excision, Platelet-Rich Plasma, and In-office Superficial Photon X-ray Radiation Therapy.

Authors:  Michael E Jones; Cherrell Hardy; Julie Ridgway
Journal:  Adv Skin Wound Care       Date:  2016-07       Impact factor: 2.347

7.  Necrotic Erythema Nodosum Leprosum Healing with Extensive Scars.

Authors:  Chandra S Sirka; Maitreyee Panda; Swetalina Pradhan; Manas R Baisakh
Journal:  Indian Dermatol Online J       Date:  2017 Nov-Dec

Review 8.  A Review of Current Keloid Management: Mainstay Monotherapies and Emerging Approaches.

Authors:  Emily E Limmer; Donald A Glass
Journal:  Dermatol Ther (Heidelb)       Date:  2020-07-23

9.  Keloid risk in patients with atopic dermatitis: a nationwide retrospective cohort study in Taiwan.

Authors:  Ying-Yi Lu; Chun-Ching Lu; Wei-Wen Yu; Li Zhang; Qing-Rui Wang; Cong-Liang Zhang; Chieh-Hsin Wu
Journal:  BMJ Open       Date:  2018-07-18       Impact factor: 2.692

10.  Risk of cancer development in patients with keloids.

Authors:  Ying-Yi Lu; Hung-Pin Tu; Chieh-Hsin Wu; Chien-Hui Hong; Kuo-Chia Yang; Hui-Ju Yang; Kee-Lung Chang; Chih-Hung Lee
Journal:  Sci Rep       Date:  2021-04-30       Impact factor: 4.379

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