Literature DB >> 215326

Tandem integration of complete and defective SV40 genomes in mouse-human somatic cell hybrids.

M S Campo, I R Cameron, M E Rogers.   

Abstract

We have analyzed the arrangement of SV40 DNA sequences integrated in human chromosome 7 in two lines of mouse-human somatic cell hybrids: one containing only one human chromosome 7 per cell and the other containing an average of about three. We found that the integration site differs in both the viral and host sequences in the two clones. However, the sites of integration into the several copies of human chromosome 7 of one clone are identical. Each chromosome 7 in both clones carries approximately six viral genomes tandemly linked. Some of these genomes lack about 20% of the DNA from the late region, including the Eco RI site.

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Year:  1978        PMID： 215326     DOI： 10.1016/0092-8674(78)90065-x

Source DB:  PubMed          Journal:  Cell        ISSN： 0092-8674            Impact factor:   41.582


  18 in total

1.  Molecular characterization of a common fragile site (FRA7H) on human chromosome 7 by the cloning of a simian virus 40 integration site.

Authors:  D Mishmar; A Rahat; S W Scherer; G Nyakatura; B Hinzmann; Y Kohwi; Y Mandel-Gutfroind; J R Lee; B Drescher; D E Sas; H Margalit; M Platzer; A Weiss; L C Tsui; A Rosenthal; B Kerem
Journal:  Proc Natl Acad Sci U S A       Date:  1998-07-07       Impact factor: 11.205

2.  A series of vectors that simplify mammalian gene targeting.

Authors:  A J Brookes; B J Stevenson; D J Porteous; J R Dorin
Journal:  Transgenic Res       Date:  1993-07       Impact factor: 2.788

3.  Characterization of a gene encoding a 115 K super T antigen expressed by a SV40-transformed rat cell line.

Authors:  E May; J M Jeltsch; F Gannon
Journal:  Nucleic Acids Res       Date:  1981-08-25       Impact factor: 16.971

Review 4.  Human cell transformation by simian virus 40--a review.

Authors:  G H Sack
Journal:  In Vitro       Date:  1981-01

5.  Integration site of polyoma virus DNA in the inducible LPT line of polyoma-transformed rat cells.

Authors:  E Mendelsohn; N Baran; A Neer; H Manor
Journal:  J Virol       Date:  1982-01       Impact factor: 5.103

6.  Rescue of a tk-plasmid from transgenic mice reveals its episomal transmission.

Authors:  U Kiessling; K Becker; M Strauss; J Schoeneich; E Geissler
Journal:  Mol Gen Genet       Date:  1986-08

7.  Integration pattern of human JC virus sequences in two clones of a cell line established from a JC virus-induced hamster brain tumor.

Authors:  W S Wold; M Green; J K Mackey; J D Martin; B L Padgett; D L Walker
Journal:  J Virol       Date:  1980-03       Impact factor: 5.103

8.  Patterns of viral DNA integration in cells transformed by wild type or DNA-binding protein mutants of adenovirus type 5 and effect of chemical carcinogens on integration.

Authors:  K Dorsch-Häsler; P B Fisher; I B Weinstein; H S Ginsberg
Journal:  J Virol       Date:  1980-05       Impact factor: 5.103

9.  Brain tumors of owl monkeys inoculated with JC virus contain the JC virus genome.

Authors:  N R Miller; P E McKeever; W London; B L Padgett; D L Walker; W C Wallen
Journal:  J Virol       Date:  1984-03       Impact factor: 5.103

10.  Introduction and recovery of a selectable bacterial gene from the genome of mammalian cells.

Authors:  M L Breitman; L C Tsui; M Buchwald; L Siminovitch
Journal:  Mol Cell Biol       Date:  1982-08       Impact factor: 4.272
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