Literature DB >> 21531145

In vitro investigation of aortic valve annuloplasty using prosthetic ring devices.

Michael Scharfschwerdt1, Mareike Pawlik, Hans-Hinrich Sievers, Efstratios I Charitos.   

Abstract

OBJECTIVES: The remodeling of the dilatated valve annulus with a prosthetic ring for the repair of valve insufficiency is a well-established concept in mitral valve surgery, and may also be suitable for aortic valve reconstruction. In this study, two models of prosthetic aortic annuloplasty devices were investigated.
METHODS: Fresh porcine aortic roots (n=16) were investigated in a pulsatile flow simulator after patch dilatation of the annulus and subsequent reconstruction using both an external and an internal prosthetic ring. For each configuration, leakage was determined by ultrasonic flow measurements and leaflet co-aptation by transesophageal echocardiography. In addition, valves' motions were recorded by high-speed video.
RESULTS: By the use of the prosthetic annuloplasty rings, leakage volumes decreased significantly compared with the dilatated root, more pronounced with the intra-annular ring. Similarly, the co-aptation height of the leaflets increased. Pressure gradients were not significantly influenced by the ring application, but leaflet motion patterns changed from the usual trapezoid to a more rectangular opening characteristic, visible at both echocardiographic and high-speed video analysis.
CONCLUSIONS: The reconstruction of a dilatated aortic valve annulus using external and internal ring devices is feasible and effective for reduction of regurgitation at which the internal ring provides a greater potential to decrease valve insufficiency.
Copyright © 2011 European Association for Cardio-Thoracic Surgery. Published by Elsevier B.V. All rights reserved.

Entities:  

Mesh:

Year:  2011        PMID: 21531145     DOI: 10.1016/j.ejcts.2011.02.073

Source DB:  PubMed          Journal:  Eur J Cardiothorac Surg        ISSN: 1010-7940            Impact factor:   4.191


  4 in total

Review 1.  Annular management during aortic valve repair: a systematic review.

Authors:  Takashi Kunihara
Journal:  Gen Thorac Cardiovasc Surg       Date:  2015-11-25

2.  Anatomy of the aortic root: implications for valve-sparing surgery.

Authors:  Efstratios I Charitos; Hans-Hinrich Sievers
Journal:  Ann Cardiothorac Surg       Date:  2013-01

3.  Anatomy and pathophysiology of the ventriculo-aortic junction: implication in aortic valve repair surgery.

Authors:  Laurent de Kerchove; Gebrine El Khoury
Journal:  Ann Cardiothorac Surg       Date:  2013-01

Review 4.  Aortic valve repair update.

Authors:  Tatsuhiko Komiya
Journal:  Gen Thorac Cardiovasc Surg       Date:  2015-02-05
  4 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.