| Literature DB >> 21530283 |
M Perona1, O Pontiggia, M Carpano, L Thomasz, S Thorp, E Pozzi, M Simian, S Kahl, G Juvenal, M Pisarev, A Dagrosa.
Abstract
The aim of these studies was to evaluate the mechanisms of cellular response to DNA damage induced by BNCT. Thyroid carcinoma cells were incubated with (10)BPA or (10)BOPP and irradiated with thermal neutrons. The surviving fraction, the cell cycle distribution and the expression of p53 and Ku70 were analyzed. Different cellular responses were observed for each irradiated group. The decrease of Ku70 in the neutrons +BOPP group could play a role in the increase of sensitization to radiation. Copyright ÂEntities:
Mesh：
Year: 2011 PMID： 21530283 DOI： 10.1016/j.apradiso.2011.03.044
Source DB: PubMed Journal: Appl Radiat Isot ISSN： 0969-8043 Impact factor: 1.513