Literature DB >> 21530136

Sepsis-associated takotsubo cardiomyopathy can be reversed with levosimendan.

Marios Karvouniaris1, John Papanikolaou, Demosthenes Makris, Epameinondas Zakynthinos.   

Abstract

Sepsis is a stressful physical condition, and at the acute phase, overstimulation of the sympathetic nervous system may occur; these events have the potential to induce cardiomyopathy. Takotsubo cardiomyopathy (TTC) is a form of catecholamine-induced cardiomyopathy, which occurs very rarely in sepsis. However, TTC management in critically ill patients with sepsis may be challenging because the use of exogenous catecholamines for circulatory support might augment further TTC. Herein, we report a rare case of TTC after urosepsis; and we point out that cardiac function may improve after catecholamine withdrawal and the application of calcium channel sensitizer levosimendan.

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Year:  2011        PMID: 21530136     DOI: 10.1016/j.ajem.2011.02.030

Source DB:  PubMed          Journal:  Am J Emerg Med        ISSN: 0735-6757            Impact factor:   2.469


  3 in total

Review 1.  Left Ventricular Dysfunction in the Setting of Takotsubo Cardiomyopathy: A Review of Clinical Patterns and Practical Implications.

Authors:  Kenan Yalta; Mustafa Yilmaztepe; Cafer Zorkun
Journal:  Card Fail Rev       Date:  2018-05

2.  High levels of circulating epinephrine trigger apical cardiodepression in a β2-adrenergic receptor/Gi-dependent manner: a new model of Takotsubo cardiomyopathy.

Authors:  Alexander R Lyon; Sian E Harding; Helen Paur; Peter T Wright; Markus B Sikkel; Matthew H Tranter; Catherine Mansfield; Peter O'Gara; Daniel J Stuckey; Viacheslav O Nikolaev; Ivan Diakonov; Laura Pannell; Haibin Gong; Hong Sun; Nicholas S Peters; Mario Petrou; Zhaolun Zheng; Julia Gorelik
Journal:  Circulation       Date:  2012-06-25       Impact factor: 29.690

3.  Takotsubo Cardiomyopathy in a Nonagenarian With Urosepsis.

Authors:  Selin Sendil; Isha Shrimanker; Keerthi Yarlagadda; Binita Bhandari; Vinod K Nookala
Journal:  Cureus       Date:  2020-06-22
  3 in total

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