Literature DB >> 2152964

Structure of germ line immunoglobulin alpha heavy-chain RNA and its location on polysomes.

G Radcliffe1, Y C Lin, M Julius, K B Marcu, J Stavnezer.   

Abstract

We describe the structure of the major germ line RNA transcribed from unrearranged immunoglobulin alpha heavy-chain genes in immunoglobulin M-expressing cells of the I.29 mu B-cell lymphoma, a cell line capable of switching to immunoglobulin A expression upon lipopolysaccharide treatment. This germ line alpha RNA has a small open reading frame that does not include the C alpha domain, and this RNA appears to be present on polysomes in I.29 mu cells.

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Year:  1990        PMID： 2152964      PMCID： PMC360760          DOI： 10.1128/mcb.10.1.382-386.1990

Source DB:  PubMed          Journal:  Mol Cell Biol        ISSN： 0270-7306            Impact factor:   4.272


  24 in total

1.  Ovalbumin messenger ribonucleic acid translation. Comparable rates of polypeptide initiation and elongation on ovalbumin and globin messenger ribonucleic acid in a rabbit reticulocyte lysate.

Authors:  R D Palmiter
Journal:  J Biol Chem       Date:  1973-03-25       Impact factor: 5.157

2.  C mu-containing transcripts initiate heterogeneously within the IgH enhancer region and contain a novel 5'-nontranslatable exon.

Authors:  G G Lennon; R P Perry
Journal:  Nature       Date:  1985 Dec 5-11       Impact factor: 49.962

3.  Messenger ribonucleoprotein particles in developing sea urchin embryos.

Authors:  E M Young; R A Raff
Journal:  Dev Biol       Date:  1979-09       Impact factor: 3.582

4.  "A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity". Addendum.

Authors:  A P Feinberg; B Vogelstein
Journal:  Anal Biochem       Date:  1984-02       Impact factor: 3.365

5.  Selection of initiation sites by eucaryotic ribosomes: effect of inserting AUG triplets upstream from the coding sequence for preproinsulin.

Authors:  M Kozak
Journal:  Nucleic Acids Res       Date:  1984-05-11       Impact factor: 16.971

6.  Point mutations define a sequence flanking the AUG initiator codon that modulates translation by eukaryotic ribosomes.

Authors:  M Kozak
Journal:  Cell       Date:  1986-01-31       Impact factor: 41.582

7.  5' flanking region of immunoglobulin heavy chain constant region genes displays length heterogeneity in germlines of inbred mouse strains.

Authors:  K B Marcu; J Banerji; N A Penncavage; R Lang; N Arnheim
Journal:  Cell       Date:  1980-11       Impact factor: 41.582

8.  Initiation of translation of the cauliflower mosaic virus genome from a polycistronic mRNA: evidence from deletion mutagenesis.

Authors:  L K Dixon; T Hohn
Journal:  EMBO J       Date:  1984-12-01       Impact factor: 11.598

9.  The murine immunoglobulin alpha gene expresses multiple transcripts from a unique membrane exon.

Authors:  C J Word; J F Mushinski; P W Tucker
Journal:  EMBO J       Date:  1983       Impact factor: 11.598

10.  Induction of immunoglobulin isotype switching in cultured I.29 B lymphoma cells. Characterization of the accompanying rearrangements of heavy chain genes.

Authors:  J Stavnezer; S Sirlin; J Abbott
Journal:  J Exp Med       Date:  1985-03-01       Impact factor: 14.307
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  15 in total

1.  Sequences of human immunoglobulin switch regions: implications for recombination and transcription.

Authors:  F C Mills; J S Brooker; R D Camerini-Otero
Journal:  Nucleic Acids Res       Date:  1990-12-25       Impact factor: 16.971

2.  Structure and expression of mouse germline immunoglobulin gamma 3 heavy chain transcripts induced by the mitogen lipopolysaccharide.

Authors:  S Gerondakis; C Gaff; D J Goodman; R J Grumont
Journal:  Immunogenetics       Date:  1991       Impact factor: 2.846

Review 3.  CD40:CD40L interactions in X-linked and non-X-linked hyper-IgM syndromes.

Authors:  A Bhushan; L R Covey
Journal:  Immunol Res       Date:  2001       Impact factor: 2.829

4.  Regulation of the antibody class switch to IgA.

Authors:  Y C Lin; P Shockett; J Stavnezer
Journal:  Immunol Res       Date:  1991       Impact factor: 2.829

5.  Overlapping activation-induced cytidine deaminase hotspot motifs in Ig class-switch recombination.

Authors:  Li Han; Shahnaz Masani; Kefei Yu
Journal:  Proc Natl Acad Sci U S A       Date:  2011-06-27       Impact factor: 11.205

Review 6.  A transcriptional serenAID: the role of noncoding RNAs in class switch recombination.

Authors:  William T Yewdell; Jayanta Chaudhuri
Journal:  Int Immunol       Date:  2017-04-01       Impact factor: 4.823

7.  Germ-line human epsilon heavy chain gene RNA transcripts utilize the full range of alternative 3' splicing seen in productive epsilon mRNA.

Authors:  K Zhang; D Diaz-Sanchez; A Saxon
Journal:  Immunology       Date:  1995-06       Impact factor: 7.397

8.  Replacement of germ-line epsilon promoter by gene targeting alters control of immunoglobulin heavy chain class switching.

Authors:  L Xu; B Gorham; S C Li; A Bottaro; F W Alt; P Rothman
Journal:  Proc Natl Acad Sci U S A       Date:  1993-04-15       Impact factor: 11.205

9.  IgA class switch in I alpha exon-deficient mice. Role of germline transcription in class switch recombination.

Authors:  G R Harriman; A Bradley; S Das; P Rogers-Fani; A C Davis
Journal:  J Clin Invest       Date:  1996-01-15       Impact factor: 14.808

10.  A selective defect in IgG2b switching as a result of targeted mutation of the I gamma 2b promoter and exon.

Authors:  J Zhang; A Bottaro; S Li; V Stewart; F W Alt
Journal:  EMBO J       Date:  1993-09       Impact factor: 11.598
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