Literature DB >> 21528469

Aortic arch repair: let it beat!

A Rüffer1, C Klopsch, F Münch, U Gottschalk, T S Mir, J Weil, H C Reichenspurner, R A Cesnjevar.   

Abstract

Objective aortic arch repair (AAR) on the beating heart may reduce cross-clamping times and offer improved postoperative cardiac function.Methods A single-center review of all patients (n = 24) who underwent surgical AAR during biventricular repair between 01/2006 and 01/2008 was done. All patients were operated on under cardiopulmonary bypass (CPB) with antegrade cerebral perfusion (ACP). During AAR, 13 patients (group 1) received cardioplegic arrest, and were compared to 11 patients (group 2) who underwent a beating-heart modification with selective myocardial perfusion. Seventeen patients had additional intracardiac lesions and underwent simultaneous correction during the procedure.Results Durations of CPB, AAR and ACP did not differ statistically between groups. Cardioplegic arrest time was significantly lower in group 1 (34 ± 13 vs. 76 ± 11 min, p = 0.02) and resulted in a subsequent reduction of myocardial ischemic damage as borne out by lower postoperative levels of troponin T and CK-MB (2.5 ± 0.7 vs. 7.1 ± 1.4 ng/mL, p = 0.02; 68.7 ± 11.5 vs. 149.1 ± 27.2 U/l, p = 0.03). We observed an enhanced patient recovery with shorter inotropic and ventilatory support times (p < 0.05).Conclusion Pediatric aortic arch correction on a CPB beating heart with selective myocardial perfusion is technically feasible and safe. The reduction of the myocardial ischemic time is effective and results in less myocardial damage. Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.

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Year:  2011        PMID: 21528469     DOI: 10.1055/s-0030-1271042

Source DB:  PubMed          Journal:  Thorac Cardiovasc Surg        ISSN: 0171-6425            Impact factor:   1.827


  2 in total

Review 1.  Goal-directed-perfusion in neonatal aortic arch surgery.

Authors:  Robert Anton Cesnjevar; Ariawan Purbojo; Frank Muench; Joerg Juengert; André Rueffer
Journal:  Transl Pediatr       Date:  2016-07

2.  Aortic arch obstruction neonates with biventricular physiology: left-open compared to closed inter-atrial communication during primary repair--a retrospective study.

Authors:  André Rüffer; Caroline Bechtold; Ariawan Purbojo; Okan Toka; Martin Glöckler; Sven Dittrich; Robert Anton Cesnjevar
Journal:  J Cardiothorac Surg       Date:  2015-04-17       Impact factor: 1.637

  2 in total

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