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Literature DB >> 21527942

Tubular biomarkers to assess progression of diabetic nephropathy.

Abstract

Despite aggressive management, many patients with diabetic nephropathy still develop end-stage renal disease. Accompanying tubulointerstitial damage is important in the progression of diabetic nephropathy. Markers of tubular damage, such as NGAL, KIM-1, and LFABP, have been proposed for monitoring the effectiveness of therapy. However, Nielsen et al. report a lack of an independent correlation between these biomarkers and glomerular filtration rate. Therefore, these markers seem to offer no improvement in the management of diabetic nephropathy.

Entities: Disease Gene Species

Mesh：

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Year: 2011 PMID： 21527942 DOI： 10.1038/ki.2011.9

Source DB: PubMed Journal: Kidney Int ISSN： 0085-2538 Impact factor: 10.612

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Cited

13 in total

1. Empagliflozin Attenuates Renal and Urinary Markers of Tubular Epithelial Cell Injury in Streptozotocin-induced Diabetic Rats.

Authors: Zahra Ashrafi Jigheh; Amir Ghorbani Haghjo; Hassan Argani; Leila Roshangar; Nadereh Rashtchizadeh; Davoud Sanajou; Saeed Nazari Soltan Ahmad; Jalil Rashedi; Siavoush Dastmalchi; Mehran Mesgari Abbasi
Journal: Indian J Clin Biochem Date: 2018-09-17

2. Association of urinary KIM-1, L-FABP, NAG and NGAL with incident end-stage renal disease and mortality in American Indians with type 2 diabetes mellitus.

Authors: Gudeta D Fufaa; E Jennifer Weil; Robert G Nelson; Robert L Hanson; Joseph V Bonventre; Venkata Sabbisetti; Sushrut S Waikar; Theodore E Mifflin; Xiaoming Zhang; Dawei Xie; Chi-Yuan Hsu; Harold I Feldman; Josef Coresh; Ramachandran S Vasan; Paul L Kimmel; Kathleen D Liu
Journal: Diabetologia Date: 2014-10-15 Impact factor: 10.122

3. MMP-9- and NMDA receptor-mediated mechanism of diabetic renovascular remodeling and kidney dysfunction: hydrogen sulfide is a key modulator.

Authors: Sourav Kundu; Sathnur Pushpakumar; Utpal Sen
Journal: Nitric Oxide Date: 2015-02-07 Impact factor: 4.427

4. Urinary N-acetyl-beta-d-glucosaminidase (NAG) with neutrophil gelatinase-associated lipocalin (NGAL) improves the diagnostic value for proximal tubule damage in diabetic kidney disease.

Authors: Khalid Siddiqui; Basim Al-Malki; Teena Puthiyaparampil George; Shaik Sarfaraz Nawaz; Khalid Al Rubeaan
Journal: 3 Biotech Date: 2019-02-04 Impact factor: 2.406

5. Cyclophilin A (CyPA) as a Novel Biomarker for Early Detection of Diabetic Nephropathy in an Animal Model.

Authors: Abdallah Mahmoud El-Ebidi; Tahia H Saleem; Mohamed Gamal El-Din Saadi; Hala Abdallah Mahmoud; Zeinab Mohamed; Hoda S Sherkawy
Journal: Diabetes Metab Syndr Obes Date: 2020-10-20 Impact factor: 3.168

Review 6. Review and discussion of tubular biomarkers in the diagnosis and management of diabetic nephropathy.

Authors: Gianfranco Tramonti; Yashpal S Kanwar
Journal: Endocrine Date: 2012-10-20 Impact factor: 3.633

7. Increased Urine IgM and IgG(2) Levels, Indicating Decreased Glomerular Size Selectivity, Are Not Affected by Dalteparin Therapy in Patients with Type 2 Diabetes.

Authors: Ole Torffvit; Majid Kalani; Jan Apelqvist; Björn Eliasson; Jan W Eriksson; Kerstin Brismar; Gun Jörneskog
Journal: Biochem Res Int Date: 2012-02-12