Literature DB >> 21525952

MicroRNA therapeutics.

J A Broderick1, P D Zamore.   

Abstract

MicroRNAs (miRNAs) provide new therapeutic targets for many diseases, while their myriad roles in development and cellular processes make them fascinating to study. We still do not fully understand the molecular mechanisms by which miRNAs regulate gene expression nor do we know the complete repertoire of mRNAs each miRNA regulates. However, recent progress in the development of effective strategies to block miRNAs suggests that anti-miRNA drugs may soon be used in the clinic.

Entities:  

Mesh：

Substances：

Year:  2011        PMID： 21525952      PMCID： PMC3237828          DOI： 10.1038/gt.2011.50

Source DB:  PubMed          Journal:  Gene Ther        ISSN： 0969-7128            Impact factor:   5.250


  67 in total

1.  MicroRNA targeting specificity in mammals: determinants beyond seed pairing.

Authors:  Andrew Grimson; Kyle Kai-How Farh; Wendy K Johnston; Philip Garrett-Engele; Lee P Lim; David P Bartel
Journal:  Mol Cell       Date:  2007-07-06       Impact factor: 17.970

2.  The human cytomegalovirus microRNA miR-UL112 acts synergistically with a cellular microRNA to escape immune elimination.

Authors:  Daphna Nachmani; Dikla Lankry; Dana G Wolf; Ofer Mandelboim
Journal:  Nat Immunol       Date:  2010-08-08       Impact factor: 25.606

3.  Most mammalian mRNAs are conserved targets of microRNAs.

Authors:  Robin C Friedman; Kyle Kai-How Farh; Christopher B Burge; David P Bartel
Journal:  Genome Res       Date:  2008-10-27       Impact factor: 9.043

4.  Prevention of interferon-stimulated gene expression using microRNA-designed hairpins.

Authors:  M Bauer; N Kinkl; A Meixner; E Kremmer; M Riemenschneider; H Förstl; T Gasser; M Ueffing
Journal:  Gene Ther       Date:  2008-08-14       Impact factor: 5.250

Review 5.  Micromanipulating cancer: microRNA-based therapeutics?

Authors:  Fabio Petrocca; Judy Lieberman
Journal:  RNA Biol       Date:  2009-07-14       Impact factor: 4.652

6.  Coexpression of Argonaute-2 enhances RNA interference toward perfect match binding sites.

Authors:  Sven Diederichs; Stephanie Jung; S Michael Rothenberg; Gromoslaw A Smolen; Barbara G Mlody; Daniel A Haber
Journal:  Proc Natl Acad Sci U S A       Date:  2008-06-30       Impact factor: 11.205

7.  MicroRNA 21 promotes glioma invasion by targeting matrix metalloproteinase regulators.

Authors:  Galina Gabriely; Thomas Wurdinger; Santosh Kesari; Christine C Esau; Julja Burchard; Peter S Linsley; Anna M Krichevsky
Journal:  Mol Cell Biol       Date:  2008-06-30       Impact factor: 4.272

Review 8.  microRNAs and cancer: an overview.

Authors:  Pedro P Medina; Frank J Slack
Journal:  Cell Cycle       Date:  2008-08-17       Impact factor: 4.534

Review 9.  MicroRNAs: target recognition and regulatory functions.

Authors:  David P Bartel
Journal:  Cell       Date:  2009-01-23       Impact factor: 41.582

10.  let-7 regulates self renewal and tumorigenicity of breast cancer cells.

Authors:  Fengyan Yu; Herui Yao; Pengcheng Zhu; Xiaoqin Zhang; Qiuhui Pan; Chang Gong; Yijun Huang; Xiaoqu Hu; Fengxi Su; Judy Lieberman; Erwei Song
Journal:  Cell       Date:  2007-12-14       Impact factor: 41.582
View more
  165 in total

1.  Transforming growth factor-β induces microRNA-29b to promote murine alveolar macrophage dysfunction after bone marrow transplantation.

Authors:  Racquel Domingo-Gonzalez; Carol A Wilke; Steven K Huang; Yasmina Laouar; Jeanette P Brown; Christine M Freeman; Jeffrey L Curtis; Gregory A Yanik; Bethany B Moore
Journal:  Am J Physiol Lung Cell Mol Physiol       Date:  2014-10-31       Impact factor: 5.464

2.  Regulation of Collagen V Expression and Epithelial-Mesenchymal Transition by miR-185 and miR-186 during Idiopathic Pulmonary Fibrosis.

Authors:  Guang-Sheng Lei; Hannah L Kline; Chao-Hung Lee; David S Wilkes; Chen Zhang
Journal:  Am J Pathol       Date:  2016-07-05       Impact factor: 4.307

Review 3.  Targeting long non-coding RNA to therapeutically upregulate gene expression.

Authors:  Claes Wahlestedt
Journal:  Nat Rev Drug Discov       Date:  2013-06       Impact factor: 84.694

Review 4.  MicroRNAs and other non-coding RNAs as targets for anticancer drug development.

Authors:  Hui Ling; Muller Fabbri; George A Calin
Journal:  Nat Rev Drug Discov       Date:  2013-11       Impact factor: 84.694

5.  MicroRNA-144-3p inhibits cell proliferation and induces cell apoptosis in prostate cancer by targeting CEP55.

Authors:  Hao Zheng; Zhenyu Guo; Xiaoqing Zheng; Weijie Cheng; Xing Huang
Journal:  Am J Transl Res       Date:  2018-08-15       Impact factor: 4.060

6.  Transcriptomic studies provide insights into the tumor suppressive role of miR-146a-5p in non-small cell lung cancer (NSCLC) cells.

Authors:  Joseph R Iacona; Nicholas J Monteleone; Alexander D Lemenze; Ashley L Cornett; Carol S Lutz
Journal:  RNA Biol       Date:  2019-08-23       Impact factor: 4.652

7.  Delivery of Exogenous miR-124 to Glioblastoma Multiform Cells by Wharton's Jelly Mesenchymal Stem Cells Decreases Cell Proliferation and Migration, and Confers Chemosensitivity.

Authors:  S Sharif; M H Ghahremani; M Soleimani
Journal:  Stem Cell Rev Rep       Date:  2018-04       Impact factor: 5.739

Review 8.  Contribution of bioinformatics prediction in microRNA-based cancer therapeutics.

Authors:  Jasjit K Banwait; Dhundy R Bastola
Journal:  Adv Drug Deliv Rev       Date:  2014-11-06       Impact factor: 15.470

9.  Synthesis, Functionalization, and Characterization of Fusogenic Porous Silicon Nanoparticles for Oligonucleotide Delivery.

Authors:  Byungji Kim; Michael J Sailor
Journal:  J Vis Exp       Date:  2019-04-16       Impact factor: 1.355

10.  IGF-I receptor as an emerging potential molecular-targeted for hepatocellular carcinoma in vitro and in vivo.

Authors:  Min Yao; Li Wang; Junling Yang; Xiaodi Yan; Yin Cai; Dengfu Yao
Journal:  Tumour Biol       Date:  2016-09-13
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.