BACKGROUND:Absorbable synthetic biopolymers have been used as bone filler in Periodontology, proving effective stimulants to bone regeneration. AIM: Copolymerized polylactic and polyglycolic acid is used as a bone filler and polyglactin 910 as a guided tissue regeneration (GTR) membrane to achieve regeneration in periodontal infrabony defects. MATERIALS AND METHODS:Forty patients with two- or three-walled infrabony defects were selected and randomly divided into two groups. Group A included patients treated with polylactic-polyglycolic acids 50:50 (Fisiograft ,Ghimsa SPA,Via Fucini, Italy) alone and Group B included patients treated with polylactic-polyglycolic acids (PLA-PGA)50:50 in conjunction with polyglactin acid 910 (Vicryl Mesh Johnson&Johnson , U.S.A ). Evaluation of clinical parameters probing depth and attachment level and radiographs was done preoperatively and 12 and 24 weeks postoperatively. RESULTS: Both the groups showed statistically significant mean reduction in probing depth and gain in clinical attachment level and linear bone fill. CONCLUSIONS: Within the limit of this study, both the treatment modalities are beneficial for the treatment of infrabony defects.
RCT Entities:
BACKGROUND: Absorbable synthetic biopolymers have been used as bone filler in Periodontology, proving effective stimulants to bone regeneration. AIM: Copolymerized polylactic and polyglycolic acid is used as a bone filler and polyglactin 910 as a guided tissue regeneration (GTR) membrane to achieve regeneration in periodontal infrabony defects. MATERIALS AND METHODS: Forty patients with two- or three-walled infrabony defects were selected and randomly divided into two groups. Group A included patients treated with polylactic-polyglycolic acids 50:50 (Fisiograft ,Ghimsa SPA,Via Fucini, Italy) alone and Group B included patients treated with polylactic-polyglycolic acids (PLA-PGA)50:50 in conjunction with polyglactin acid 910 (Vicryl Mesh Johnson&Johnson , U.S.A ). Evaluation of clinical parameters probing depth and attachment level and radiographs was done preoperatively and 12 and 24 weeks postoperatively. RESULTS: Both the groups showed statistically significant mean reduction in probing depth and gain in clinical attachment level and linear bone fill. CONCLUSIONS: Within the limit of this study, both the treatment modalities are beneficial for the treatment of infrabony defects.
Authors: G Castillo-Dalí; R Castillo-Oyagüe; A Batista-Cruzado; C López-Santos; A Rodríguez-González-Elipe; J-L Saffar; C-D Lynch; J-L Gutiérrez-Pérez; D Torres-Lagares Journal: Med Oral Patol Oral Cir Bucal Date: 2017-03-01