PURPOSE: Individuals with mild traumatic brain injury (mTBI) frequently complain of increased sensitivity to visual motion. Thus, the purpose of this study was to assess the coherent motion threshold (CMT) in subjects with mTBI and reported visual motion sensitivity. METHODS: Fourteen adult subjects with mTBI and symptoms of motion sensitivity were tested. They were compared with 40 age-matched asymptomatic visually normal individuals. CMT was assessed using a 2-alternative, forced choice paradigm. A symptom rating-scale questionnaire related to motion and light sensitivity, vertigo, and self-reported reading ability was also administered to the mTBI group. RESULTS: Mean CMTs were significantly elevated in the mTBI (8.81%) versus the normal subjects (6.53%). There was a trend for a progressive increase in mean CMT in mTBI with increased symptoms related to visual motion sensitivity and vertigo. However, there was no apparent relation to either light sensitivity or self-reported reading ability in mTBI. There was no significant age effect in either group. CONCLUSIONS: The elevated CMT in mTBI suggests damage to the magnocellular pathway, such as extrastriate visual cortical area V5, visual area medial temporal, and the medial superior temporal cortex, which is involved directly in various aspects of motion processing. These findings are consistent with the subjects' symptoms of motion sensitivity and vertigo in their natural environments.
PURPOSE: Individuals with mild traumatic brain injury (mTBI) frequently complain of increased sensitivity to visual motion. Thus, the purpose of this study was to assess the coherent motion threshold (CMT) in subjects with mTBI and reported visual motion sensitivity. METHODS: Fourteen adult subjects with mTBI and symptoms of motion sensitivity were tested. They were compared with 40 age-matched asymptomatic visually normal individuals. CMT was assessed using a 2-alternative, forced choice paradigm. A symptom rating-scale questionnaire related to motion and light sensitivity, vertigo, and self-reported reading ability was also administered to the mTBI group. RESULTS: Mean CMTs were significantly elevated in the mTBI (8.81%) versus the normal subjects (6.53%). There was a trend for a progressive increase in mean CMT in mTBI with increased symptoms related to visual motion sensitivity and vertigo. However, there was no apparent relation to either light sensitivity or self-reported reading ability in mTBI. There was no significant age effect in either group. CONCLUSIONS: The elevated CMT in mTBI suggests damage to the magnocellular pathway, such as extrastriate visual cortical area V5, visual area medial temporal, and the medial superior temporal cortex, which is involved directly in various aspects of motion processing. These findings are consistent with the subjects' symptoms of motion sensitivity and vertigo in their natural environments.
Authors: Marousa Pavlou; Susan L Whitney; Abdulaziz A Alkathiry; Marian Huett; Linda M Luxon; Ewa Raglan; Emma L Godfrey; Doris-Eva Bamiou Journal: Front Neurol Date: 2017-12-05 Impact factor: 4.003
Authors: Ann Mansur; Tyler M Hauer; Mohammed Wasif Hussain; Mohammed K Alatwi; Apameh Tarazi; Mozhgan Khodadadi; Charles H Tator Journal: J Neurotrauma Date: 2018-08-15 Impact factor: 5.269