| Literature DB >> 21524583 |
K Liaras1, A Geronikaki, J Glamočlija, A Cirić, M Soković.
Abstract
As part of ongoing studies in developing new antimicrobials, we report the synthesis of a new class of structurally novel derivatives, that incorporate two known bioactive structures a thiazole and chalcone, to yield a class of compounds with interesting antimicrobial properties. Evaluation of antibacterial activity showed that almost all the compounds exhibited greater activity than reference drugs and thus could be promising novel drug candidates.Entities:
Mesh：
Substances：
Year: 2011 PMID： 21524583 DOI： 10.1016/j.bmc.2011.04.007
Source DB: PubMed Journal: Bioorg Med Chem ISSN： 0968-0896 Impact factor: 3.641