Literature DB >> 21524082

A concise approach for the total synthesis of pseudolaric acid A.

Tao Xu1, Chuang-chuang Li, Zhen Yang.   

Abstract

A new strategy for the stereoselective total synthesis of natural product pseudolaric acid A (1) was accomplished in 16 steps from commercially available starting material, featuring a samarium diiodide (SmI(2))-mediated intramolecular alkene-ketyl radical cyclization and a ring-closing metathesis (RCM) reaction to stereoselectively cast the unusual trans-fused [5-7]-bicyclic core of pseudolaric acid A (1).

Entities:  

Mesh：

Substances：

Year:  2011        PMID： 21524082     DOI： 10.1021/ol200741j

Source DB:  PubMed          Journal:  Org Lett        ISSN： 1523-7052            Impact factor:   6.005


  4 in total

1.  Isolation, Structure, and Total Synthesis of the Marine Macrolide Mangrolide D.

Authors:  Junyu Gong; Wei Li; Peng Fu; John MacMillan; Jef K De Brabander
Journal:  Org Lett       Date:  2019-04-08       Impact factor: 6.005

2.  A unified approach to the daucane and sphenolobane bicyclo[5.3.0]decane core: enantioselective total syntheses of daucene, daucenal, epoxydaucenal B, and 14-para-anisoyloxydauc-4,8-diene.

Authors:  Nathan B Bennett; Brian M Stoltz
Journal:  Chemistry       Date:  2013-12-02       Impact factor: 5.236

Review 3.  Application of Pauson-Khand reaction in the total synthesis of terpenes.

Authors:  Majid M Heravi; Leila Mohammadi
Journal:  RSC Adv       Date:  2021-11-29       Impact factor: 4.036

4.  Synthetic studies toward longeracemine: a SmI2-mediated spirocyclization and rearrangement cascade to construct the 2-azabicyclo[2.2.1]heptane framework.

Authors:  Keita Komine; Kyle M Lambert; Quentin R Savage; Joshua B Cox; John L Wood
Journal:  Chem Sci       Date:  2020-07-30       Impact factor: 9.825
  4 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.