| Literature DB >> 21523300 |
Anthony J Atkin1, Jason M Lynam, Benjamin E Moulton, Philip Sawle, Roberto Motterlini, Nicola M Boyle, Mary T Pryce, Ian J S Fairlamb.
Abstract
The deoxy-myoglobin (deoxy-Mb)/carbonmonoxy-myoglobin (Mb-CO) UV-vis assay is the principal method used for quantifying the rates of CO release from CO-releasing molecules (CO-RMs) that might possess therapeutic benefits. Some issues emerge when the Mb-CO assay is utilized for testing CO-RMs with novel structures, which are comprehensively discussed here for the first time. Two methods for processing raw UV-vis spectroscopic data generated from the assay are presented in this paper.Mesh:
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Year: 2011 PMID: 21523300 DOI: 10.1039/c0dt01809k
Source DB: PubMed Journal: Dalton Trans ISSN: 1477-9226 Impact factor: 4.390