Literature DB >> 21522489

A microfluidic platform for on-demand formation and merging of microdroplets using electric control.

Hao Gu1, Chandrashekhar U Murade, Michael H G Duits, Frieder Mugele.   

Abstract

We discuss a microfluidic system in which (programmable) local electric fields originating from embedded and protected electrodes are used to control the formation and merging of droplets in a microchannel. The creation of droplets-on-demand (DOD) is implemented using the principle of electrowetting. Combined with hydrodynamic control, the droplet size and formation frequency can be varied independently. Using two synchronized DOD injectors, merging-on-demand (MOD) is achieved via electrocoalescence. The efficiency of MOD is 98% based on hundreds of observations. These two functionalities can be activated independently.

Year:  2011        PMID： 21522489      PMCID： PMC3082336          DOI： 10.1063/1.3570666

Source DB:  PubMed          Journal:  Biomicrofluidics        ISSN： 1932-1058            Impact factor:   2.800


  19 in total

1.  Controlled microfluidic encapsulation of cells, proteins, and microbeads in lipid vesicles.

Authors:  Yung-Chieh Tan; Kanaka Hettiarachchi; Maria Siu; Yen-Ru Pan; Abraham Phillip Lee
Journal:  J Am Chem Soc       Date:  2006-05-03       Impact factor: 15.419

2.  Electrocoalescence mechanisms of microdroplets using localized electric fields in microfluidic channels.

Authors:  Michele Zagnoni; Guillaume Le Lain; Jonathan M Cooper
Journal:  Langmuir       Date:  2010-09-21       Impact factor: 3.882

3.  High-throughput automated droplet microfluidic system for screening of reaction conditions.

Authors:  Krzysztof Churski; Piotr Korczyk; Piotr Garstecki
Journal:  Lab Chip       Date:  2010-02-16       Impact factor: 6.799

4.  Droplet fusion by alternating current (AC) field electrocoalescence in microchannels.

Authors:  Max Chabert; Kevin D Dorfman; Jean-Louis Viovy
Journal:  Electrophoresis       Date:  2005-10       Impact factor: 3.535

5.  Mechanism for flow-rate controlled breakup in confined geometries: a route to monodisperse emulsions.

Authors:  Piotr Garstecki; Howard A Stone; George M Whitesides
Journal:  Phys Rev Lett       Date:  2005-04-27       Impact factor: 9.161

Review 6.  Reactions in droplets in microfluidic channels.

Authors:  Helen Song; Delai L Chen; Rustem F Ismagilov
Journal:  Angew Chem Int Ed Engl       Date:  2006-11-13       Impact factor: 15.336

7.  Electrowetting --a versatile tool for controlling microdrop generation.

Authors:  F Malloggi; H Gu; A G Banpurkar; S A Vanapalli; F Mugele
Journal:  Eur Phys J E Soft Matter       Date:  2008-02-20       Impact factor: 1.890

8.  Microvalve-actuated precise control of individual droplets in microfluidic devices.

Authors:  Shaojiang Zeng; Bowei Li; Xiao'ou Su; Jianhua Qin; Bingcheng Lin
Journal:  Lab Chip       Date:  2009-03-27       Impact factor: 6.799

9.  Electro-coalescence of digitally controlled droplets.

Authors:  Xize Niu; Fabrice Gielen; Andrew J deMello; Joshua B Edel
Journal:  Anal Chem       Date:  2009-09-01       Impact factor: 6.986

10.  Electrically initiated upstream coalescence cascade of droplets in a microfluidic flow.

Authors:  Michele Zagnoni; Charles N Baroud; Jonathan M Cooper
Journal:  Phys Rev E Stat Nonlin Soft Matter Phys       Date:  2009-10-02
View more
  7 in total

1.  Electrocoalescence based serial dilution of microfluidic droplets.

Authors:  Biddut Bhattacharjee; Siva A Vanapalli
Journal:  Biomicrofluidics       Date:  2014-07-29       Impact factor: 2.800

2.  Microfluidic channel structures speed up mixing of multiple emulsions by a factor of ten.

Authors:  Kevin J Land; Mesuli Mbanjwa; Jan G Korvink
Journal:  Biomicrofluidics       Date:  2014-09-02       Impact factor: 2.800

Review 3.  Droplets formation and merging in two-phase flow microfluidics.

Authors:  Hao Gu; Michel H G Duits; Frieder Mugele
Journal:  Int J Mol Sci       Date:  2011-04-15       Impact factor: 5.923

Review 4.  Enhanced single-cell encapsulation in microfluidic devices: From droplet generation to single-cell analysis.

Authors:  Si Da Ling; Yuhao Geng; An Chen; Yanan Du; Jianhong Xu
Journal:  Biomicrofluidics       Date:  2020-12-22       Impact factor: 2.800

5.  Microfluidic Chamber Design for Controlled Droplet Expansion and Coalescence.

Authors:  Mark Kielpinski; Oliver Walther; Jialan Cao; Thomas Henkel; J Michael Köhler; G Alexander Groß
Journal:  Micromachines (Basel)       Date:  2020-04-10       Impact factor: 2.891

6.  A Liquid-Metal-Based Dielectrophoretic Microdroplet Generator.

Authors:  Ronghang Wang; Lunjia Zhang; Meng Gao; Qifu Wang; Zhongshan Deng; Lin Gui
Journal:  Micromachines (Basel)       Date:  2019-11-11       Impact factor: 2.891

7.  Dual dean entrainment with volume ratio modulation for efficient droplet co-encapsulation: extreme single-cell indexing.

Authors:  Jack Harrington; Luis Blay Esteban; Jonathan Butement; Andres F Vallejo; Simon I R Lane; Bhavwanti Sheth; Maaike S A Jongen; Rachel Parker; Patrick S Stumpf; Rosanna C G Smith; Ben D MacArthur; Matthew J J Rose-Zerilli; Marta E Polak; Tim Underwood; Jonathan West
Journal:  Lab Chip       Date:  2021-07-09       Impact factor: 7.517
  7 in total

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