| Literature DB >> 21520897 |
Shi-Hui Dong1, Chuan-Rui Zhang, Cheng-Hui Xu, Jian Ding, Jian-Min Yue.
Abstract
Nine new daphnane-type diterpenoids (1-9), named trigohownins A-I, and four known analogues were isolated from Trigonostemon howii. Their structures were elucidated on the basis of extensive NMR and MS analyses. Trigohownins A (1) and D (4) exhibited moderate cytotoxic activity against the HL-60 tumor cell line, with IC50 values of 17.0 and 9.3 μM, respectively.Entities:
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Year: 2011 PMID: 21520897 DOI: 10.1021/np200231u
Source DB: PubMed Journal: J Nat Prod ISSN: 0163-3864 Impact factor: 4.050