Literature DB >> 21520897

Daphnane-type diterpenoids from Trigonostemon howii.

Shi-Hui Dong1, Chuan-Rui Zhang, Cheng-Hui Xu, Jian Ding, Jian-Min Yue.   

Abstract

Nine new daphnane-type diterpenoids (1-9), named trigohownins A-I, and four known analogues were isolated from Trigonostemon howii. Their structures were elucidated on the basis of extensive NMR and MS analyses. Trigohownins A (1) and D (4) exhibited moderate cytotoxic activity against the HL-60 tumor cell line, with IC50 values of 17.0 and 9.3 μM, respectively.

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Year:  2011        PMID: 21520897     DOI: 10.1021/np200231u

Source DB:  PubMed          Journal:  J Nat Prod        ISSN: 0163-3864            Impact factor:   4.050


  1 in total

Review 1.  Discovery of structurally diverse and bioactive compounds from plant resources in China.

Authors:  Sheng-Ping Yang; Jian-Min Yue
Journal:  Acta Pharmacol Sin       Date:  2012-09-03       Impact factor: 6.150

  1 in total

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