Literature DB >> 21520600

[Effective reversal of muscle relaxation by rocuronium using sugammadex in a patient with myasthenia gravis undergoing laparoscopic cholecystectomy].

Nobuyasu Komasawa1, Hideki Noma, Takashi Sugi, Norihiko Sukenaga, Hideki Kakiuchi.   

Abstract

As myasthenia gravis affects neuromuscular transmission, these patients show various responses to neuromuscular blocking drugs. We report a successful use of the sugammadex in a myasthenic patient to reverse rocuronium-induced neuromuscular block. A 69-year-old woman was scheduled for laparoscopic cholecystectomy and total of rocuronium 20 mg was administered. After spontaneous recovery of T1, we administered sugammadex 200mg intravenously, reversing neuromuscular blockade to a train-of-four ratio (T4/T1) of 100% within 30 sec. Sugammadex can be used to reverse rocuronium-induced neuromuscular blockade in patients with myasthenia gravis, thereby avoiding the need for reversal with acetylcholinesterase inhibitors.

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Year:  2011        PMID: 21520600

Source DB:  PubMed          Journal:  Masui        ISSN: 0021-4892


  3 in total

1.  Rapid Return of Spontaneous Respiration after General Anesthesia with Sugammadex in a Patient with Myasthenia Gravis.

Authors:  Raing Kyu Kim; Soon Yul Kim
Journal:  J Lifestyle Med       Date:  2016-03-31

2.  Effects of Combined Rocuronium and Cisatracurium in Laparoscopic Cholecystectomy.

Authors:  Woo Young Park; Kwang Ho Lee; Young Bok Lee; Myeong Hoon Kim; Hyun Kyo Lim; Jong Bum Choi
Journal:  J Lifestyle Med       Date:  2017-01-31

3.  Feasibility of full and rapid neuromuscular blockade recovery with sugammadex in myasthenia gravis patients undergoing surgery - a series of 117 cases.

Authors:  Tomas Vymazal; Martina Krecmerova; Vladimír Bicek; Robert Lischke
Journal:  Ther Clin Risk Manag       Date:  2015-10-15       Impact factor: 2.423

  3 in total

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