Literature DB >> 2152054

A study of 31 patients with easy bruising from University Hospital, Kuala Lumpur.

N S Chin1, P L Koong.   

Abstract

Thirty one patients were investigated for the main complaint of easy bruising. These patients had normal platelet count with no past history of immune thrombocytopenia or systemic disorders known to predispose to bruising and a negative drug history. The evaluation of these patients included clinical review (history and physical examination) plus coagulation tests consisting of bleeding time, prothrombin time, partial thromboplastin time, thrombin time, fibrinogen level, FXIII screen and platelet functions test. Seven of the paediatric patients had acquired platelet dysfunction with eosinophilia (APDE). In 17 (94.4%) of the 18 adult patients no abnormality was demonstrated. Hence APDE was the commonest cause of easy bruising in children while the haemostatic defect contributing to easy bruising in adults remained unknown.

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Year:  1990        PMID: 2152054

Source DB:  PubMed          Journal:  Med J Malaysia        ISSN: 0300-5283


  2 in total

1.  Eosinophil Granulocyte and NK Cell-Mediated Platelet Destruction in Immune Thrombocytopenia.

Authors:  Shuguo Wang; Fenghai Liu; Hongguo Zhao
Journal:  Indian J Hematol Blood Transfus       Date:  2017-05-17       Impact factor: 0.900

2.  Unusual hematologic disease affecting Caucasian children traveling to Southeast Asia: acquired platelet dysfunction with eosinophilia.

Authors:  Anselm Chi-Wai Lee
Journal:  Hematol Rep       Date:  2012-02-08
  2 in total

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