Literature DB >> 21518425

Genetics of atopic dermatitis.

Caroline Bussmann1, Stephan Weidinger, Natalija Novak.   

Abstract

Atopic dermatitis (AD) is a multifactorial disease, with a strong genetic predisposition. Genome-wide studies as well as candidate gene studies revealed several susceptibility loci. Since the observation of a strong association of "loss of function" mutations in the filaggrin gene with AD, the epidermal barrier was rediscovered as important pathophysiological co-factor of this disease.
© The Authors • Journal compilation © Blackwell Verlag GmbH, Berlin.

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Year:  2011        PMID： 21518425     DOI： 10.1111/j.1610-0387.2011.07656.x

Source DB:  PubMed          Journal:  J Dtsch Dermatol Ges        ISSN： 1610-0379            Impact factor:   5.584


  10 in total

1.  Changes in immunological profile as a function of urbanization and lifestyle.

Authors:  Moustapha Mbow; Sanne E de Jong; Lynn Meurs; Souleymane Mboup; Tandakha Ndiaye Dieye; Katja Polman; Maria Yazdanbakhsh
Journal:  Immunology       Date:  2014-12       Impact factor: 7.397

Review 2.  The genetics of human skin disease.

Authors:  Gina M DeStefano; Angela M Christiano
Journal:  Cold Spring Harb Perspect Med       Date:  2014-10-01       Impact factor: 6.915

3.  DNA methylation of the filaggrin gene adds to the risk of eczema associated with loss-of-function variants.

Authors:  A H Ziyab; W Karmaus; J W Holloway; H Zhang; S Ewart; S H Arshad
Journal:  J Eur Acad Dermatol Venereol       Date:  2012-09-25       Impact factor: 6.166

4.  Association of HLA-DRB1 genetic variants with the persistence of atopic dermatitis.

Authors:  David J Margolis; Nandita Mitra; Brian Kim; Jayanta Gupta; Ole J Hoffstad; Maryte Papadopoulos; Bradley Wubbenhorst; Katherine L Nathanson; Jamie L Duke; Dimitri S Monos; Malek Kamoun
Journal:  Hum Immunol       Date:  2015-08-22       Impact factor: 2.850

5.  Gene expression in the skin of dogs sensitized to the house dust mite Dermatophagoides farinae.

Authors:  Paz Schamber; Rachel Schwab-Richards; Stefan Bauersachs; Ralf S Mueller
Journal:  G3 (Bethesda)       Date:  2014-08-05       Impact factor: 3.154

Review 6.  Genetic risk factors for the development of allergic disease identified by genome-wide association.

Authors:  M A Portelli; E Hodge; I Sayers
Journal:  Clin Exp Allergy       Date:  2015-01       Impact factor: 5.018

7.  Exome sequencing of filaggrin and related genes in African-American children with atopic dermatitis.

Authors:  David J Margolis; Jayanta Gupta; Andrea J Apter; Ole Hoffstad; Maryte Papadopoulos; Tim R Rebbeck; Bradley Wubbenhorst; Nandita Mitra
Journal:  J Invest Dermatol       Date:  2014-03-07       Impact factor: 8.551

8.  Dysbiotic Lesional Microbiome With Filaggrin Missense Variants Associate With Atopic Dermatitis in India.

Authors:  Shankha Nath; Naina Kumari; Debabrata Bandyopadhyay; Neloy Sinha; Partha P Majumder; Rupak Mitra; Souvik Mukherjee
Journal:  Front Cell Infect Microbiol       Date:  2020-11-17       Impact factor: 5.293

Review 9.  Resolving the etiology of atopic disorders by using genetic analysis of racial ancestry.

Authors:  Jayanta Gupta; Elisabet Johansson; Jonathan A Bernstein; Ranajit Chakraborty; Gurjit K Khurana Hershey; Marc E Rothenberg; Tesfaye B Mersha
Journal:  J Allergy Clin Immunol       Date:  2016-06-11       Impact factor: 10.793

10.  Interactive effect of STAT6 and IL13 gene polymorphisms on eczema status: results from a longitudinal and a cross-sectional study.

Authors:  Ali H Ziyab; Gwyneth A Davies; Susan Ewart; Julian M Hopkin; Eric M Schauberger; Marsha Wills-Karp; John W Holloway; Syed Hasan Arshad; Hongmei Zhang; Wilfried Karmaus
Journal:  BMC Med Genet       Date:  2013-07-02       Impact factor: 2.103
  10 in total

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