| Literature DB >> 215176 |
Abstract
High density lipoprotein (HDL) was found in vitro to form myelin buds (liposomes) from washed crystals of free cholesterol (commercial or atheroma sources). This activity led to the progressive destruction and solubilization of the crystals. Low density and very low density lipoproteins did not have any effect. Liposome formation and solubilization were accelerated by calcium ions, phospholipase A and polyunsaturated lecithin (Lipostabil). Cholesterol crystals were nearly completely destroyed after 18 h incubation with HDL-Lipostabil.Entities:
Mesh:
Substances:
Year: 1978 PMID: 215176 DOI: 10.1016/0021-9150(78)90142-9
Source DB: PubMed Journal: Atherosclerosis ISSN: 0021-9150 Impact factor: 5.162