| Literature DB >> 21517112 |
Ji-Ya Fu1, Qing-Chuan Yang, Qi-Lin Wang, Jun-Nan Ming, Fei-Ying Wang, Xiao-Ying Xu, Li-Xin Wang.
Abstract
A series of simple chiral primary amino acids were first successfully applied to promote the enantioselective α-amination of branched aldehydes with azadicarboxylates and the desired adducts bearing quaternary stereogenic centers were obtained in excellent yields (up to 99%) and enantioselectivities (up to 97% ee).Entities:
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Year: 2011 PMID： 21517112 DOI： 10.1021/jo102361h
Source DB: PubMed Journal: J Org Chem ISSN： 0022-3263 Impact factor: 4.354