Literature DB >> 215171

Glycosaminoglycan-lipoprotein complexes from aortas of hypercholesterolemic rabbits. Part 1. Isolation and characterization.

T P Mawhinney, J M Augustyn, K E Fritz.   

Abstract

Glycosaminoglycan-lipoprotein complexes were isolated from rabbit aortas exhibiting nearly confluent cholesterol-induced foam cell lesions by extraction with 0.15 M NaCl. Purification and characterization was achieved by gel chromatography, non-ionic differential flotation and by cellulose polyacetate electrophoresis. Analysis showed that these complexes consisted of very low density lipoproteins, heparan sulfate, chondroitin sulfate-C and hyaluronic acid. The demonstration that rabbit intimal foam cell lesions contain extractable glycosaminoglycan-lipoprotein complexes makes this animal model an excellent tool for further studies on the role of these complexes in the atherogenic process.

Entities:  

Mesh：

Substances：

Year:  1978        PMID： 215171     DOI： 10.1016/0021-9150(78)90161-2

Source DB:  PubMed          Journal:  Atherosclerosis        ISSN： 0021-9150            Impact factor:   5.162


  10 in total

1.  Monoclonal antibodies recognizing lipid-laden cells and extracellular regions with lipid-deposits in atherosclerotic aorta.

Authors:  J Kimura; K Nakagami; K Amanuma; S Ohkuma; Y Yoshida; T Takano
Journal:  Virchows Arch A Pathol Anat Histopathol       Date:  1986

2.  Lipoprotein and albumin accumulation in reendothelialized and deendothelialized aorta.

Authors:  D J Falcone; D P Hajjar; C R Minick
Journal:  Am J Pathol       Date:  1984-01       Impact factor: 4.307

3.  Unesterified cholesterol-rich lipid particles in atherosclerotic lesions of human and rabbit aortas.

Authors:  F F Chao; L M Amende; E J Blanchette-Mackie; S I Skarlatos; W Gamble; J H Resau; W T Mergner; H S Kruth
Journal:  Am J Pathol       Date:  1988-04       Impact factor: 4.307

4.  Monoclonal antibody EMR1a/212D recognizing site of deposition of extracellular lipid in atherosclerosis: purification and characterization of the antigen.

Authors:  K Nakagami; O Shimazaki; R Sato; Y Komine; S Ohkuma; T Takano
Journal:  Am J Pathol       Date:  1989-07       Impact factor: 4.307

5.  Cardiovascular Risk and Serum Hyaluronic Acid: A Preliminary Study in a Healthy Population of Low/Intermediate Risk.

Authors:  Chrysanthi Papanastasopoulou; Maria Papastamataki; Petros Karampatsis; Eleni Anagnostopoulou; Ioannis Papassotiriou; Nikolaos Sitaras
Journal:  J Clin Lab Anal       Date:  2016-06-16       Impact factor: 2.352

6.  Distribution patterns of apolipoproteins A1, A2, and B in the wall of atherosclerotic vessels.

Authors:  E Vollmer; J Brust; A Roessner; A Bosse; F Burwikel; B Kaesberg; B Harrach; H Robenek; W Böcker
Journal:  Virchows Arch A Pathol Anat Histopathol       Date:  1991

7.  Effect of endothelium on glycosaminoglycan accumulation in injured rabbit aorta.

Authors:  T N Wight; K D Curwen; M M Litrenta; D R Alonso; C R Minick
Journal:  Am J Pathol       Date:  1983-11       Impact factor: 4.307

8.  Lipoprotein-proteoglycan complexes induce continued cholesteryl ester accumulation in foam cells from rabbit atherosclerotic lesions.

Authors:  P Vijayagopal; S R Srinivasan; J H Xu; E R Dalferes; B Radhakrishnamurthy; G S Berenson
Journal:  J Clin Invest       Date:  1993-03       Impact factor: 14.808

9.  Enhancement of cholesterol and cholesteryl ester accumulation in re-endothelialized aorta.

Authors:  D J Falcone; D P Hajjar; C R Minick
Journal:  Am J Pathol       Date:  1980-04       Impact factor: 4.307

10.  Lipoprotein-heparin-fibronectin-denatured collagen complexes enhance cholesteryl ester accumulation in macrophages.

Authors:  D J Falcone; N Mated; H Shio; C R Minick; S D Fowler
Journal:  J Cell Biol       Date:  1984-10       Impact factor: 10.539
  10 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.