Literature DB >> 21516339

Spectral study of interaction between poly(L-lysine)-poly(ethylene glycol)-poly(L-lysine) and nucleic acids.

Yu He1, Qiujun Yan, Gongwu Song, Juan Chen.   

Abstract

Polymer-DNA interactions have attracted considerable interests due to their important application in DNA transfection and cellular drug delivery technologies. In this work, a new detection assay for DNA is proposed with a tri-block copolymer poly(L-lysine)-poly(ethylene glycol)-poly(L-lysine) by resonance light scattering technique with the linear ranges from 0.0656 to 6.56 μg ml⁻¹. The detection limit for DNA is 0.42 ng ml⁻¹. Most coexisting substances do not interfere in the detection. UV-spectra and FTIR-spectra were employed to demonstrate the mechanisms of the interaction that the conformation of the DNA changes because the microenvironment of DNA changes.

Entities:  

Mesh：

Substances：

Year:  2011        PMID： 21516339     DOI： 10.1007/s10856-011-4314-7

Source DB:  PubMed          Journal:  J Mater Sci Mater Med        ISSN： 0957-4530            Impact factor:   3.896


  20 in total

1.  Binding and uptake of cationic lipid:pDNA complexes by polarized airway epithelial cells.

Authors:  Q Chu; J D Tousignant; S Fang; C Jiang; L H Chen; S H Cheng; R K Scheule; S J Eastman
Journal:  Hum Gene Ther       Date:  1999-01-01       Impact factor: 5.695

2.  Salt effect on the interactions between gemini surfactant and oppositely charged polyelectrolyte in aqueous solution.

Authors:  Yingying Pi; Yazhuo Shang; Honglai Liu; Ying Hu; Jianwen Jiang
Journal:  J Colloid Interface Sci       Date:  2006-11-20       Impact factor: 8.128

3.  Structural and thermodynamic features of complexes formed by DNA and synthetic polynucleotides with dodecylamine and dodecyltrimethylammonium bromide.

Authors:  A I Petrov; D N Khalil; R L Kazaryan; I V Savintsev; B I Sukhorukov
Journal:  Bioelectrochemistry       Date:  2002-11       Impact factor: 5.373

4.  Intratracheal administration of interleukin 12 plasmid-cationic lipid complexes inhibits murine lung metastases.

Authors:  P Blezinger; B D Freimark; M Matar; E Wilson; A Singhal; W Min; J L Nordstrom; F Pericle
Journal:  Hum Gene Ther       Date:  1999-03-20       Impact factor: 5.695

5.  Physical properties and in vitro transfection efficiency of gene delivery vectors based on complexes of DNA with synthetic polycations.

Authors:  Tomás Reschel; Cestmír Konák; David Oupický; Leonard W Seymour; Karel Ulbrich
Journal:  J Control Release       Date:  2002-05-17       Impact factor: 9.776

6.  Characterization of a targeted gene carrier, lactose-polyethylene glycol-grafted poly-L-lysine and its complex with plasmid DNA.

Authors:  Y H Choi; F Liu; J S Choi; S W Kim; J S Park
Journal:  Hum Gene Ther       Date:  1999-11-01       Impact factor: 5.695

7.  Remarkable increase in nuclease resistance of plasmid DNA through supramolecular assembly with poly(ethylene glycol)-poly(L-lysine) block copolymer.

Authors:  S Katayose; K Kataoka
Journal:  J Pharm Sci       Date:  1998-02       Impact factor: 3.534

8.  Nonionic polymeric micelles for oral gene delivery in vivo.

Authors:  Shwu-Fen Chang; Han-Yi Chang; Yaw-Chong Tong; Sy-Hann Chen; Fei-Chin Hsaio; Shao-Chun Lu; Jiahorng Liaw
Journal:  Hum Gene Ther       Date:  2004-05       Impact factor: 5.695

9.  Resonance light scattering study on the interaction between quinidine sulfate and congo red and its analytical application.

Authors:  Yanbo Zeng; Liling Cai; Haidong Wang; Lei Li; Weijing You; Longhua Guo; Guonan Chen
Journal:  Luminescence       Date:  2010 Jan-Feb       Impact factor: 2.464

10.  Self-assembly of polyamine-poly(ethylene glycol) copolymers with phosphorothioate oligonucleotides.

Authors:  S V Vinogradov; T K Bronich; A V Kabanov
Journal:  Bioconjug Chem       Date:  1998 Nov-Dec       Impact factor: 4.774
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.