Kristen W Maloney1, Sarah H Kagan. 1. Rhoads Three Inpatient Oncology Unit, Hospital of University of Pennsylvania, Philadelphia, PA, USA.
Abstract
OBJECTIVE: Oral antineoplastic agents offer multiple advantages in cancer therapies. Thus, understanding issues of adherence to these agents for older adults becomes critical to successful comprehensive care of the older cancer patient. DATA SOURCES: This analysis of adherence to oral agents among older cancer patients draws on interdisciplinary geriatric and oncologic research reports and clinical reviews. CONCLUSION: Older adults are at increased risk for poor adherence to oral agents. Barriers to adherence are diverse. Problems emerge from age-related physical changes, comorbid conditions, polypharmacy, and drug interactions. Psychosocial barriers include limited insurance coverage and transportation problems to social isolation and inadequate social support. IMPLICATION FOR NURSING PRACTICE: Nurses should lead interdisciplinary, individualized plans of care to mitigate barriers and support adherence to cancer therapy.
OBJECTIVE: Oral antineoplastic agents offer multiple advantages in cancer therapies. Thus, understanding issues of adherence to these agents for older adults becomes critical to successful comprehensive care of the older cancerpatient. DATA SOURCES: This analysis of adherence to oral agents among older cancerpatients draws on interdisciplinary geriatric and oncologic research reports and clinical reviews. CONCLUSION: Older adults are at increased risk for poor adherence to oral agents. Barriers to adherence are diverse. Problems emerge from age-related physical changes, comorbid conditions, polypharmacy, and drug interactions. Psychosocial barriers include limited insurance coverage and transportation problems to social isolation and inadequate social support. IMPLICATION FOR NURSING PRACTICE: Nurses should lead interdisciplinary, individualized plans of care to mitigate barriers and support adherence to cancer therapy.
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