Debra Barton1. 1. Oncology, Mayo Clinic, 200 First Street SW, Charlton 6-133, Rochester, MN 55905, USA. barton.debra@mayo.edu
Abstract
OBJECTIVES: To review oral agents approved for cancer, discuss their mechanism of action and/or molecular targets, and outline side effects and challenges that impact adherence. DATA SOURCES: Peer reviewed literature and on-line drug information. CONCLUSION: Oral agents to treat cancer, although not new, are common and increasing dramatically. The context of adherence to oral agents is complicated by increased knowledge of food-drug interactions and combinations of agents with overlapping or synergistic toxicity profiles. IMPLICATIONS FOR NURSING PRACTICE: The role of nursing in the administration and education of oral cancer treatments is critical to optimal treatment outcomes.
OBJECTIVES: To review oral agents approved for cancer, discuss their mechanism of action and/or molecular targets, and outline side effects and challenges that impact adherence. DATA SOURCES: Peer reviewed literature and on-line drug information. CONCLUSION: Oral agents to treat cancer, although not new, are common and increasing dramatically. The context of adherence to oral agents is complicated by increased knowledge of food-drug interactions and combinations of agents with overlapping or synergistic toxicity profiles. IMPLICATIONS FOR NURSING PRACTICE: The role of nursing in the administration and education of oral cancer treatments is critical to optimal treatment outcomes.
Authors: Pearman D Parker; Sue P Heiney; Daniela B Friedman; Tisha M Felder; Robin Dawson Estrada; Eboni Herbert Harris; Swann Arp Adams Journal: J Nurs Educ Pract Date: 2018-01-16
Authors: Jamie M Jacobs; Molly E Ream; Nicole Pensak; Lauren E Nisotel; Joel N Fishbein; James J MacDonald; Joanne Buzaglo; Inga T Lennes; Steven A Safren; William F Pirl; Jennifer S Temel; Joseph A Greer Journal: J Natl Compr Canc Netw Date: 2019-03-01 Impact factor: 11.908
Authors: Stefan Feiten; Rudolf Weide; Vera Friesenhahn; Jochen Heymanns; Kristina Kleboth; Hubert Köppler; Christoph van Roye; Jörg Thomalla Journal: Springerplus Date: 2016-03-03