| Literature DB >> 21512633 |
Philippe Renaudier1, Syvie Schlanger, Mai-Phuong Vo Mai, Nadra Ounnoughene, Pascal Breton, Stéphane Cheze, Albane Girard, Lisette Hauser, Jean François Legras, Hélène Odent-Malaure, Danielle Rebibo, Chantal Waller, Béatrice Willaert, Cyril Caldani.
Abstract
SUMMARY: The French Hemovigilance Network has been established in 1994 and records all adverse events associated with the transfusion of a labile blood products (LBP) regardless of their severity. From 1994 to 2006 35,423,172 LBP were issued, 85,812 adverse transfusion reactions notified, and 139 cases of transfusion related acute lung injury (TRALI) observed. The LBP most at risk is fresh frozen plasma (FFP), followed by platelets concentrates (PC) and packed red cells (PRC). However, because the use of FFP is not frequent in France, it only accounts for about 10% of TRALI, whereas PRC and PC are involved in the remaining cases. In no case, pooled FFP treated with solvent-detergent were involved. Patients' profiles are peculiar with a high disease burden. Therefore, targeting a prevention policy only on FFP would result in a marginal reduction of TRALI in France.Entities:
Year: 2008 PMID： 21512633 PMCID： PMC3076340 DOI： 10.1159/000117812
Source DB: PubMed Journal: Transfus Med Hemother ISSN： 1660-3796 Impact factor: 3.747