Literature DB >> 21512236

Hepatic oxidoreduction-related genes are upregulated by administration of hydrogen-saturated drinking water.

Yuji Nakai1, Bunpei Sato, Shota Ushiama, Shinji Okada, Keiko Abe, Soichi Arai.   

Abstract

The effects of the administration of molecular hydrogen-saturated drinking water (hydrogen water) on hepatic gene expression were investigated in rats. Using DNA microarrays, 548 upregulated and 695 downregulated genes were detected in the liver after 4 weeks of administration of hydrogen water. Gene Ontology analysis revealed that genes for oxidoreduction-related proteins, including hydroxymethylglutaryl CoA reductase, were significantly enriched in the upregulated genes.

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Year:  2011        PMID： 21512236     DOI： 10.1271/bbb.100819

Source DB:  PubMed          Journal:  Biosci Biotechnol Biochem        ISSN： 0916-8451            Impact factor:   2.043


  12 in total

1.  Simultaneous oral and inhalational intake of molecular hydrogen additively suppresses signaling pathways in rodents.

Authors:  Sayaka Sobue; Kazuaki Yamai; Mikako Ito; Kinji Ohno; Masafumi Ito; Takashi Iwamoto; Shanlou Qiao; Tetsuo Ohkuwa; Masatoshi Ichihara
Journal:  Mol Cell Biochem       Date:  2015-02-24       Impact factor: 3.396

Review 2.  Hydrogen treatment: a novel option in liver diseases.

Authors:  Jian Shi; Brittany Duncan; Xuyuan Kuang
Journal:  Clin Med (Lond)       Date:  2021-03       Impact factor: 2.659

Review 3.  Molecular hydrogen as an emerging therapeutic medical gas for neurodegenerative and other diseases.

Authors:  Kinji Ohno; Mikako Ito; Masatoshi Ichihara; Masafumi Ito
Journal:  Oxid Med Cell Longev       Date:  2012-06-08       Impact factor: 6.543

Review 4.  Molecular hydrogen: new antioxidant and anti-inflammatory therapy for rheumatoid arthritis and related diseases.

Authors:  Toru Ishibashi
Journal:  Curr Pharm Des       Date:  2013       Impact factor: 3.116

5.  Molecular hydrogen is involved in phytohormone signaling and stress responses in plants.

Authors:  Jiqing Zeng; Mingyong Zhang; Xuejun Sun
Journal:  PLoS One       Date:  2013-08-12       Impact factor: 3.240

Review 6.  Hydrogen as a new class of radioprotective agent.

Authors:  Liren Qian; Jianliang Shen; Yunhai Chuai; Jianming Cai
Journal:  Int J Biol Sci       Date:  2013-09-14       Impact factor: 6.580

7.  Beneficial biological effects and the underlying mechanisms of molecular hydrogen - comprehensive review of 321 original articles.

Authors:  Masatoshi Ichihara; Sayaka Sobue; Mikako Ito; Masafumi Ito; Masaaki Hirayama; Kinji Ohno
Journal:  Med Gas Res       Date:  2015-10-19

8.  Protective effects of molecular hydrogen on steroid-induced osteonecrosis in rabbits via reducing oxidative stress and apoptosis.

Authors:  Jia Li; Zhaogang Ge; Lihong Fan; Kunzheng Wang
Journal:  BMC Musculoskelet Disord       Date:  2017-02-02       Impact factor: 2.362

Review 9.  Molecular hydrogen: a preventive and therapeutic medical gas for various diseases.

Authors:  Li Ge; Ming Yang; Na-Na Yang; Xin-Xin Yin; Wen-Gang Song
Journal:  Oncotarget       Date:  2017-09-21

10.  Does H2 Alter Mitochondrial Bioenergetics via GHS-R1α Activation?

Authors:  Sergej M Ostojic
Journal:  Theranostics       Date:  2017-03-07       Impact factor: 11.556
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