Literature DB >> 21511984

Agnostic about in vivo inverse agonism of agouti-related peptide.

Malcolm J Low1.   

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Year:  2011        PMID： 21511984      PMCID： PMC3075934          DOI： 10.1210/en.2011-0232

Source DB:  PubMed          Journal:  Endocrinology        ISSN： 0013-7227            Impact factor:   4.736


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  21 in total

1.  Antagonism of central melanocortin receptors in vitro and in vivo by agouti-related protein.

Authors:  M M Ollmann; B D Wilson; Y K Yang; J A Kerns; Y Chen; I Gantz; G S Barsh
Journal:  Science       Date:  1997-10-03       Impact factor: 47.728

2.  Overexpression of Agrt leads to obesity in transgenic mice.

Authors:  M Graham; J R Shutter; U Sarmiento; I Sarosi; K L Stark
Journal:  Nat Genet       Date:  1997-11       Impact factor: 38.330

3.  Agouti-related protein functions as an inverse agonist at a constitutively active brain melanocortin-4 receptor.

Authors:  C Haskell-Luevano; E K Monck
Journal:  Regul Pept       Date:  2001-05-05

4.  AgRP(83-132) acts as an inverse agonist on the human-melanocortin-4 receptor.

Authors:  W A Nijenhuis; J Oosterom; R A Adan
Journal:  Mol Endocrinol       Date:  2001-01

5.  Preservation of eumelanin hair pigmentation in proopiomelanocortin-deficient mice on a nonagouti (a/a) genetic background.

Authors:  Andrzej Slominski; Przemyslaw M Plonka; Alexander Pisarchik; James L Smart; Virginie Tolle; Jacobo Wortsman; Malcolm J Low
Journal:  Endocrinology       Date:  2004-11-24       Impact factor: 4.736

6.  Interactions of alpha-melanotropin and agouti on B16 melanoma cells: evidence for inverse agonism of agouti.

Authors:  W Siegrist; R Drozdz; R Cotti; D H Willard; W O Wilkison; A N Eberle
Journal:  J Recept Signal Transduct Res       Date:  1997 Jan-May       Impact factor: 2.092

7.  Constitutive activity of the melanocortin-4 receptor is maintained by its N-terminal domain and plays a role in energy homeostasis in humans.

Authors:  Supriya Srinivasan; Cecile Lubrano-Berthelier; Cedric Govaerts; Franck Picard; Pamela Santiago; Bruce R Conklin; Christian Vaisse
Journal:  J Clin Invest       Date:  2004-10       Impact factor: 14.808

8.  Obesity due to proopiomelanocortin deficiency: three new cases and treatment trials with thyroid hormone and ACTH4-10.

Authors:  Heiko Krude; Heike Biebermann; Dirk Schnabel; Mojca Zerjav Tansek; Pierre Theunissen; Primus E Mullis; Annette Grüters
Journal:  J Clin Endocrinol Metab       Date:  2003-10       Impact factor: 5.958

9.  Pigmentation phenotypes of variant extension locus alleles result from point mutations that alter MSH receptor function.

Authors:  L S Robbins; J H Nadeau; K R Johnson; M A Kelly; L Roselli-Rehfuss; E Baack; K G Mountjoy; R D Cone
Journal:  Cell       Date:  1993-03-26       Impact factor: 41.582

10.  Agouti protein is an antagonist of the melanocyte-stimulating-hormone receptor.

Authors:  D Lu; D Willard; I R Patel; S Kadwell; L Overton; T Kost; M Luther; W Chen; R P Woychik; W O Wilkison
Journal:  Nature       Date:  1994-10-27       Impact factor: 49.962
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  3 in total

1.  Molecular and functional analysis of human β-defensin 3 action at melanocortin receptors.

Authors:  Matthew A Nix; Christopher B Kaelin; Tina Ta; Allison Weis; Gregory J Morton; Gregory S Barsh; Glenn L Millhauser
Journal:  Chem Biol       Date:  2013-06-20

Review 2.  Neural melanocortin receptors in obesity and related metabolic disorders.

Authors:  Clemence Girardet; Andrew A Butler
Journal:  Biochim Biophys Acta       Date:  2013-05-13

3.  Distinct glutamatergic and GABAergic subsets of hypothalamic pro-opiomelanocortin neurons revealed by in situ hybridization in male rats and mice.

Authors:  Gábor Wittmann; Erik Hrabovszky; Ronald M Lechan
Journal:  J Comp Neurol       Date:  2013-10-01       Impact factor: 3.215
  3 in total

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