Literature DB >> 21511860

Better outcomes with treatment by coiling relative to clipping of unruptured intracranial aneurysms in the United States, 2001-2008.

W Brinjikji1, A A Rabinstein, D M Nasr, G Lanzino, D F Kallmes, H J Cloft.   

Abstract

BACKGROUND AND
PURPOSE: Endovascular therapy has increasingly become an acceptable option for treatment of unruptured aneurysms. To better understand the recent trends in the use of and outcomes related to coiling compared with clipping for unruptured aneurysms in the United States, we evaluated the NIS.
MATERIALS AND METHODS: Hospitalizations for clipping or coiling of unruptured cerebral aneurysms from 2001 to 2008 were identified by cross-matching ICD codes for the diagnosis of unruptured aneurysm (437.3) with procedural codes for clipping (39.51) or coiling (39.52, 39.79, or 39.72) of cerebral aneurysms and excluding all patients with a diagnosis of subarachnoid hemorrhage (430) and intracerebral hemorrhage (431). Mortality and discharge to a long-term facility were evaluated for both clipping and coiling patient populations.
RESULTS: The fraction of unruptured aneurysms treated with coiling increased from 20% in 2001 to 63% in 2008. For surgical clipping, the percentage of patients discharged to long-term facilities was 14.0% (4184/29,918) compared with 4.9% (1655/34,125) of coiled patients (P < .0001). Clipped patients also had a higher mortality rate because 344 (1.2%) clipped patients died compared with 215 (0.6%) coiled patients (P < .0001). Between 2001 and 2008, the overall number of adverse outcomes from treatment had decreased from 14.8% to 7.6%.
CONCLUSIONS: The use of endovascular coiling relative to surgical clipping of unruptured intracranial aneurysms is associated with decreasing periprocedural morbidity and mortality among patients treated in the United States from 2001 to 2008.

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Mesh:

Year:  2011        PMID: 21511860      PMCID: PMC8013132          DOI: 10.3174/ajnr.A2453

Source DB:  PubMed          Journal:  AJNR Am J Neuroradiol        ISSN: 0195-6108            Impact factor:   3.825


  23 in total

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5.  Treatment of unruptured intracranial aneurysms: a nationwide assessment of effectiveness.

Authors:  R T Higashida; B J Lahue; M T Torbey; L N Hopkins; E Leip; D F Hanley
Journal:  AJNR Am J Neuroradiol       Date:  2007-01       Impact factor: 3.825

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9.  Characteristics of nontraumatic subarachnoid hemorrhage in the United States in 2003.

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10.  Length of stay and total hospital charges of clipping versus coiling for ruptured and unruptured adult cerebral aneurysms in the Nationwide Inpatient Sample database 2002 to 2006.

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3.  Periprocedural safety of Pipeline therapy for unruptured cerebral aneurysms: Analysis of 279 Patients in a multihospital database.

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Review 6.  Review of 2 decades of aneurysm-recurrence literature, part 2: Managing recurrence after endovascular coiling.

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7.  The effect of basilar artery bifurcation angle on rates of initial occlusion, recanalization, and retreatment of basilar artery apex aneurysms following coil embolization.

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Review 8.  Endovascular treatment of anterior communicating artery aneurysms: a systematic review and meta-analysis.

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