Literature DB >> 21509040

How does hypertension affect your eyes?

M Bhargava1, M K Ikram, T Y Wong.   

Abstract

Hypertension has profound effects on various parts of the eye. Classically, elevated blood pressure results in a series of retinal microvascular changes called hypertensive retinopathy, comprising of generalized and focal retinal arteriolar narrowing, arteriovenous nicking, retinal hemorrhages, microaneurysms and, in severe cases, optic disc and macular edema. Studies have shown that mild hypertensive retinopathy signs are common and seen in nearly 10% of the general adult non-diabetic population. Hypertensive retinopathy signs are associated with other indicators of end-organ damage (for example, left ventricular hypertrophy, renal impairment) and may be a risk marker of future clinical events, such as stroke, congestive heart failure and cardiovascular mortality. Furthermore, hypertension is one of the major risk factors for development and progression of diabetic retinopathy, and control of blood pressure has been shown in large clinical trials to prevent visual loss from diabetic retinopathy. In addition, several retinal diseases such as retinal vascular occlusion (artery and vein occlusion), retinal arteriolar emboli, macroaneurysm, ischemic optic neuropathy and age-related macular degeneration may also be related to hypertension; however, there is as yet no evidence that treatment of hypertension prevents vision loss from these conditions. In management of patients with hypertension, physicians should be aware of the full spectrum of the relationship of blood pressure and the eye.

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Year:  2011        PMID: 21509040     DOI: 10.1038/jhh.2011.37

Source DB:  PubMed          Journal:  J Hum Hypertens        ISSN: 0950-9240            Impact factor:   3.012


  29 in total

1.  [Hypertensive changes of the fundus].

Authors:  W Göbel; J Matlach
Journal:  Ophthalmologe       Date:  2013-10       Impact factor: 1.059

2.  Subconjunctival hemorrhage after intravitreal injection of anti-vascular endothelial growth factor.

Authors:  Cheolmin Yun; Jaeryung Oh; Soon-Young Hwang; Seong-Woo Kim; Kuhl Huh
Journal:  Graefes Arch Clin Exp Ophthalmol       Date:  2014-11-19       Impact factor: 3.117

3.  Ablation of Immunoproteasome β5i Subunit Suppresses Hypertensive Retinopathy by Blocking ATRAP Degradation in Mice.

Authors:  Shuai Wang; Jing Li; Tong Wang; Jie Bai; Yun-Long Zhang; Qiu-Yue Lin; Jing-Min Li; Qi Zhao; Shu-Bin Guo; Hui-Hua Li
Journal:  Mol Ther       Date:  2019-10-05       Impact factor: 11.454

4.  Retinopathy and RAAS Activation: Results From the Canadian Study of Longevity in Type 1 Diabetes.

Authors:  Julie A Lovshin; Yuliya Lytvyn; Leif E Lovblom; Alexandra Katz; Geneviève Boulet; Petter Bjornstad; Vesta Lai; Leslie Cham; Josephine Tse; Andrej Orszag; Hillary A Keenan; Narinder Paul; Vera Bril; David T Wong; Kylen D McReelis; Michael H Brent; Bruce A Perkins; David Z I Cherney
Journal:  Diabetes Care       Date:  2018-12-06       Impact factor: 19.112

5.  OTNet: A CNN Method Based on Hierarchical Attention Maps for Grading Arteriosclerosis of Fundus Images with Small Samples.

Authors:  Hang Bai; Li Gao; Xiongwen Quan; Han Zhang; Shuo Gao; Chuanze Kang; Jiaqiang Qi
Journal:  Interdiscip Sci       Date:  2021-09-18       Impact factor: 2.233

6.  Association Between Retinal Microvascular Metrics Using Optical Coherence Tomography Angiography and Carotid Artery Stenosis in a Chinese Cohort.

Authors:  Qian Xu; Hongyi Sun; Qu Yi
Journal:  Front Physiol       Date:  2022-06-03       Impact factor: 4.755

7.  Low rates of eye care utilization among visually impaired subsidized senior housing residents.

Authors:  Amanda F Elliott; Megan Heskett; Christopher Spiker; Gerald McGwin; Cynthia Owsley
Journal:  Aging Ment Health       Date:  2019-11-07       Impact factor: 3.658

Review 8.  Hypertensive eye disease.

Authors:  Carol Y Cheung; Valérie Biousse; Pearse A Keane; Ernesto L Schiffrin; Tien Y Wong
Journal:  Nat Rev Dis Primers       Date:  2022-03-10       Impact factor: 52.329

9.  Retinal imaging to identify target organ damage in older Africans: A pilot study.

Authors:  Rebecca Jones; Harry W I Putnam; Heiko Philippin; Charles Cleland; David H Steel; William K Gray; Joanna E Klaptocz; Bernadetha Swai; Richard W Walker
Journal:  J Clin Hypertens (Greenwich)       Date:  2018-07-19       Impact factor: 3.738

Review 10.  Retinal arterial hypertrophy: the new LVH?

Authors:  Kaivan Khavandi; Meena Arunakirinathan; Adam S Greenstein; Anthony M Heagerty
Journal:  Curr Hypertens Rep       Date:  2013-06       Impact factor: 5.369

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