BACKGROUND: Obesity is epidemic worldwide, and increases in cesarean delivery rates have occurred in parallel. OBJECTIVE: This study aimed to determine whether cesarean delivery is a risk factor for obesity in adulthood in a birth cohort of Brazilian subjects. DESIGN: We initiated a birth cohort study in Ribeirão Preto, southeastern Brazil, in 1978. A randomly selected sample of 2057 subjects from the original cohort was reassessed in 2002-2004. Type of delivery, birth weight, maternal smoking, and schooling were obtained after birth. The following data from subjects were collected at 23-25 y of age: body mass index (BMI; in kg/m(2)), physical activity, smoking, and income. Obesity was defined as a BMI ≥30. A Poisson multivariable model was performed to determine the association between cesarean delivery and BMI. RESULTS: The obesity rate in adults born by cesarean delivery was 15.2% and in those born by vaginal delivery was 10.4% (P = 0.002). Adults born by cesarean delivery had an increased risk (prevalence ratio: 1.58; 95% CI: 1.23, 2.02) of obesity at adulthood after adjustments. CONCLUSION: We hypothesize that increasing rates of cesarean delivery may play a role in the obesity epidemic worldwide.
BACKGROUND:Obesity is epidemic worldwide, and increases in cesarean delivery rates have occurred in parallel. OBJECTIVE: This study aimed to determine whether cesarean delivery is a risk factor for obesity in adulthood in a birth cohort of Brazilian subjects. DESIGN: We initiated a birth cohort study in Ribeirão Preto, southeastern Brazil, in 1978. A randomly selected sample of 2057 subjects from the original cohort was reassessed in 2002-2004. Type of delivery, birth weight, maternal smoking, and schooling were obtained after birth. The following data from subjects were collected at 23-25 y of age: body mass index (BMI; in kg/m(2)), physical activity, smoking, and income. Obesity was defined as a BMI ≥30. A Poisson multivariable model was performed to determine the association between cesarean delivery and BMI. RESULTS: The obesity rate in adults born by cesarean delivery was 15.2% and in those born by vaginal delivery was 10.4% (P = 0.002). Adults born by cesarean delivery had an increased risk (prevalence ratio: 1.58; 95% CI: 1.23, 2.02) of obesity at adulthood after adjustments. CONCLUSION: We hypothesize that increasing rates of cesarean delivery may play a role in the obesity epidemic worldwide.
Authors: H G Dahlen; H P Kennedy; C M Anderson; A F Bell; A Clark; M Foureur; J E Ohm; A M Shearman; J Y Taylor; M L Wright; S Downe Journal: Med Hypotheses Date: 2013-02-12 Impact factor: 1.538
Authors: Andrea E Cassidy-Bushrow; Ganesa Wegienka; Suzanne Havstad; Albert M Levin; Susan V Lynch; Dennis R Ownby; Andrew G Rundle; Kimberley J Woodcroft; Edward M Zoratti; Christine Cole Johnson Journal: Matern Child Health J Date: 2015-06
Authors: Morgan R Chojnacki; Hannah D Holscher; Alaina R Balbinot; Lauren B Raine; John R Biggan; Anne M Walk; Arthur F Kramer; Neal J Cohen; Charles H Hillman; Naiman A Khan Journal: Early Hum Dev Date: 2019-01-12 Impact factor: 2.079
Authors: Andrea E Cassidy-Bushrow; Ganesa Wegienka; Suzanne Havstad; Albert M Levin; Susan V Lynch; Dennis R Ownby; Andrew G Rundle; Kimberley J Woodcroft; Edward M Zoratti; Christine Cole Johnson Journal: Ethn Dis Date: 2016-01-21 Impact factor: 1.847