Literature DB >> 21505758

One-pot synthesis of 1,2,3-triazole linked dihydropyrimidinones via Huisgen 1,3-dipolar/Biginelli cycloaddition.

Peyman Salehi1, Minoo Dabiri, Majid Koohshari, Siyavash Kazemi Movahed, Morteza Bararjanian.   

Abstract

The combination of the Biginelli reaction with click chemistry has been used for the one-pot synthesis of 1,2,3-triazole linked dihydropyrimidinones from azides, aromatic aldehydes containing a propargyl ether group, urea, and 1,3-dicarbonyl compounds using Cu(OAc)(2)/sodium ascorbate as catalyst in acetic acid under mild reaction conditions.

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Year:  2011        PMID： 21505758     DOI： 10.1007/s11030-011-9313-6

Source DB:  PubMed          Journal:  Mol Divers        ISSN： 1381-1991            Impact factor:   2.943


  23 in total

1.  Click Chemistry: Diverse Chemical Function from a Few Good Reactions.

Authors:  Hartmuth C. Kolb; M. G. Finn; K. Barry Sharpless
Journal:  Angew Chem Int Ed Engl       Date:  2001-06-01       Impact factor: 15.336

2.  Rapid diversity-oriented synthesis in microtiter plates for in situ screening of HIV protease inhibitors.

Authors:  Ashraf Brik; John Muldoon; Ying-Chuan Lin; John H Elder; David S Goodsell; Arthur J Olson; Valery V Fokin; K Bary Sharpless; Chi-Huey Wong
Journal:  Chembiochem       Date:  2003-11-07       Impact factor: 3.164

3.  Dendronized linear polymers via "click chemistry".

Authors:  Brett Helms; Justin L Mynar; Craig J Hawker; Jean M J Fréchet
Journal:  J Am Chem Soc       Date:  2004-11-24       Impact factor: 15.419

4.  Directed DNA metallization.

Authors:  Glenn A Burley; Johannes Gierlich; Mohammad R Mofid; Hadar Nir; Shay Tal; Yoav Eichen; Thomas Carell
Journal:  J Am Chem Soc       Date:  2006-02-08       Impact factor: 15.419

5.  Combining Biginelli multicomponent and click chemistry: generation of 6-(1,2,3-triazol-1-yl)-dihydropyrimidone libraries.

Authors:  Bogdan Khanetskyy; Doris Dallinger; C Oliver Kappe
Journal:  J Comb Chem       Date:  2004 Nov-Dec

6.  Pharmacologic profile of the dihydropyrimidine calcium channel blockers SQ 32,547 and SQ 32,926 [correction of SQ 32,946].

Authors:  G J Grover; S Dzwonczyk; D M McMullen; D E Normandin; C S Parham; P G Sleph; S Moreland
Journal:  J Cardiovasc Pharmacol       Date:  1995-08       Impact factor: 3.105

7.  Organic azides: an exploding diversity of a unique class of compounds.

Authors:  Stefan Bräse; Carmen Gil; Kerstin Knepper; Viktor Zimmermann
Journal:  Angew Chem Int Ed Engl       Date:  2005-08-19       Impact factor: 15.336

Review 8.  The convergence of synthetic organic and polymer chemistries.

Authors:  Craig J Hawker; Karen L Wooley
Journal:  Science       Date:  2005-08-19       Impact factor: 47.728

9.  Bioconjugation by copper(I)-catalyzed azide-alkyne [3 + 2] cycloaddition.

Authors:  Qian Wang; Timothy R Chan; Robert Hilgraf; Valery V Fokin; K Barry Sharpless; M G Finn
Journal:  J Am Chem Soc       Date:  2003-03-19       Impact factor: 15.419

10.  Synthesis and anti-inflammatory activity of some [4,6-(4-substituted aryl)-2-thioxo-1,2,3,4-tetrahydro-pyrimidin-5-yl]-acetic acid derivatives.

Authors:  Sushilkumar S Bahekar; Devanand B Shinde
Journal:  Bioorg Med Chem Lett       Date:  2004-04-05       Impact factor: 2.823
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  1 in total

1.  Multicomponent Synthesis and Evaluation of New 1,2,3-Triazole Derivatives of Dihydropyrimidinones as Acidic Corrosion Inhibitors for Steel.

Authors:  Rodrigo González-Olvera; Viridiana Román-Rodríguez; Guillermo E Negrón-Silva; Araceli Espinoza-Vázquez; Francisco Javier Rodríguez-Gómez; Rosa Santillan
Journal:  Molecules       Date:  2016-02-22       Impact factor: 4.411
  1 in total

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