Literature DB >> 2150518

Effect of calponin on actin-activated myosin ATPase activity.

M Abe1, K Takahashi, K Hiwada.   

Abstract

Calponin inhibited the actin-activated myosin MgATPase activity in a dose-dependent manner without affecting the phosphorylation level of myosin light chain. This inhibition was Ca2(+)-independent. The decrease in enzymatic activity of myosin was correlated with binding of calponin to actin-tropomyosin filaments. Caldesmon showed a further inhibition of the calponin-induced inhibition of MgATPase activity of the thiophosphorylated myosin. Calponin-induced inhibition of the myosin MgATPase activity was reversed by the addition of calmodulin only in the presence of Ca2+. These results suggest that calponin acts as an inhibitory component of smooth muscle thin filaments.

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Year:  1990        PMID： 2150518     DOI： 10.1093/oxfordjournals.jbchem.a123289

Source DB:  PubMed          Journal:  J Biochem        ISSN： 0021-924X            Impact factor:   3.387


  38 in total

1.  Calponin interaction with alpha-actinin-actin: evidence for a structural role for calponin.

Authors:  B Leinweber; J X Tang; W F Stafford; J M Chalovich
Journal:  Biophys J       Date:  1999-12       Impact factor: 4.033

2.  The maximal velocity of vascular smooth muscle shortening is independent of the expression of calponin.

Authors:  C Facemire; F V Brozovich; J P Jin
Journal:  J Muscle Res Cell Motil       Date:  2000-05       Impact factor: 2.698

3.  A role for serine-175 in modulating the molecular conformation of calponin.

Authors:  J P Jin; M P Walsh; C Sutherland; W Chen
Journal:  Biochem J       Date:  2000-09-01       Impact factor: 3.857

4.  Smooth muscle proteins as intracellular components of the chromatophores of the Antarctic fishes Pagothenia borchgrevinki and Trematomus bernacchii (Nototheniidae).

Authors:  V B Meyer-Rochow; M Royuela; B Fraile; R Paniagua
Journal:  Protoplasma       Date:  2001       Impact factor: 3.356

Review 5.  Calponin (CaP) as a latch-bridge protein--a new concept in regulation of contractility in smooth muscles.

Authors:  Pawel T Szymanski
Journal:  J Muscle Res Cell Motil       Date:  2004       Impact factor: 2.698

6.  An emerin "proteome": purification of distinct emerin-containing complexes from HeLa cells suggests molecular basis for diverse roles including gene regulation, mRNA splicing, signaling, mechanosensing, and nuclear architecture.

Authors:  James M Holaska; Katherine L Wilson
Journal:  Biochemistry       Date:  2007-07-10       Impact factor: 3.162

7.  Mechanoregulation of h2-calponin gene expression and the role of Notch signaling.

Authors:  Wen-rui Jiang; Geoffrey Cady; M Moazzem Hossain; Qi-Quan Huang; Xin Wang; J-P Jin
Journal:  J Biol Chem       Date:  2013-11-27       Impact factor: 5.157

8.  Ca2+ regulation of the contractile apparatus in canine gastric smooth muscle.

Authors:  H Ozaki; W T Gerthoffer; M Hori; H Karaki; K M Sanders; N G Publicover
Journal:  J Physiol       Date:  1993-01       Impact factor: 5.182

9.  Deletion of calponin 2 in macrophages alters cytoskeleton-based functions and attenuates the development of atherosclerosis.

Authors:  Rong Liu; J-P Jin
Journal:  J Mol Cell Cardiol       Date:  2016-08-26       Impact factor: 5.000

10.  Two domains of interaction with calcium binding proteins can be mapped using fragments of calponin.

Authors:  F L Wills; W D McCubbin; M Gimona; P Strasser; C M Kay
Journal:  Protein Sci       Date:  1994-12       Impact factor: 6.725
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