Literature DB >> 21501076

Clinical profiles of primary open angle glaucoma versus normal tension glaucoma patients: a pilot study.

Sanjay Asrani1, Brian Samuels, Mugdha Thakur, Cecilia Santiago, Maragatha Kuchibhatla.   

Abstract

PURPOSE: To study the health profiles and behavioral differences between primary open angle glaucoma (POAG) and normal tension glaucoma (NTG) patients.
METHODS: Confidential mail survey of ICD-9 defined POAG (n = 277) and NTG (n = 116) patients was carried out to collect information regarding age, gender, height, weight, waist circumference, blood pressure (BP), medications [prescription (Rx) and over the counter (OTC)], education, and the Short Health Anxiety Inventory (SHAI).
RESULTS: NTG patients (59/116) were significantly more likely to respond to the survey than POAG patients (43/277), p = 0.0001, and to have obtained college level education (70% vs. 42%), p = 0.003. Body weight, waist circumference, body mass index, systolic BP, pulse pressure, and ratio of prescription medications to OTC medications were significantly lower in the NTG group (p < 0.0001). The SHAI score, mean age, and diastolic BP were not different between the two groups. A subgroup analysis of college-educated patients in both groups revealed persisting significant differences in waist circumference, systolic BP, and ratio of Rx to OTC medications.
CONCLUSIONS: NTG patients do not have significantly greater health anxiety than POAG patients. NTG patients are more likely to have lower BMI, systolic BP, and ratio of Rx to OTC medications than POAG patients. The pilot nature of this study limits generalizability of these findings. Larger studies confirming these findings and elucidating the role of refractive error and medical history on such differences are needed.

Entities:  

Mesh:

Year:  2011        PMID: 21501076     DOI: 10.3109/02713683.2011.559563

Source DB:  PubMed          Journal:  Curr Eye Res        ISSN: 0271-3683            Impact factor:   2.424


  6 in total

1.  Metabolic syndrome: a risk factor for high intraocular pressure in the Israeli population.

Authors:  Tamara Wygnanski-Jaffe; Itzhak Bieran; Dorit Tekes-Manova; Yair Morad; Isaac Ashkenazi; Eedy Mezer
Journal:  Int J Ophthalmol       Date:  2015-04-18       Impact factor: 1.779

2.  Body mass index has a linear relationship with cerebrospinal fluid pressure.

Authors:  John P Berdahl; David Fleischman; Jana Zaydlarova; Sandra Stinnett; R Rand Allingham; Michael P Fautsch
Journal:  Invest Ophthalmol Vis Sci       Date:  2012-03-15       Impact factor: 4.799

3.  Multiple Systemic Vascular Risk Factors Are Associated With Low-Tension Glaucoma.

Authors:  Robert O Funk; David O Hodge; Darrell Kohli; Gavin W Roddy
Journal:  J Glaucoma       Date:  2022-01-01       Impact factor: 2.290

Review 4.  The role of cerebrospinal fluid pressure in glaucoma and other ophthalmic diseases: A review.

Authors:  David Fleischman; R Rand Allingham
Journal:  Saudi J Ophthalmol       Date:  2013-03-17

5.  Is normal-tension glaucoma a risk factor for stroke?-A 10-year follow-up study.

Authors:  Meng-Sheng Lee; Li-Lin Kuo; Elise Chia-Hui Tan; Oscar K Lee
Journal:  PLoS One       Date:  2017-06-19       Impact factor: 3.240

Review 6.  New directions in the treatment of normal tension glaucoma.

Authors:  Brian J Song; Joseph Caprioli
Journal:  Indian J Ophthalmol       Date:  2014-05       Impact factor: 1.848

  6 in total

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