UNLABELLED: We evaluated a portable γ-camera for sentinel node identification during laparoscopic sentinel lymphadenectomy for prostate cancer. METHODS: We analyzed the portable γ-camera for intraoperative sentinel node visualization in 55 patients after (99m)Tc injection, preoperative planar lymphoscintigraphy, and SPECT/CT. RESULTS: Sixteen percent of 178 nodes seen on SPECT/CT could not be detected with the portable γ-camera. A seed pointer was useful for localizing sentinel nodes intraoperatively in 27% of patients. Seventeen additional sentinel nodes (2 tumor-positive nodes) were removed by monitoring after excision. The location of each sentinel node was significantly associated with the ability to detect it intraoperatively. CONCLUSION: Intraoperative imaging leads to excision of more radioactive nodes and can determine the residual radioactivity after excision. The use of a radioactive source as a pointer enables efficient identification of nodes in difficult locations (paraaortic nodes) and in patients with a high body mass index.
UNLABELLED: We evaluated a portable γ-camera for sentinel node identification during laparoscopic sentinel lymphadenectomy for prostate cancer. METHODS: We analyzed the portable γ-camera for intraoperative sentinel node visualization in 55 patients after (99m)Tc injection, preoperative planar lymphoscintigraphy, and SPECT/CT. RESULTS: Sixteen percent of 178 nodes seen on SPECT/CT could not be detected with the portable γ-camera. A seed pointer was useful for localizing sentinel nodes intraoperatively in 27% of patients. Seventeen additional sentinel nodes (2 tumor-positive nodes) were removed by monitoring after excision. The location of each sentinel node was significantly associated with the ability to detect it intraoperatively. CONCLUSION: Intraoperative imaging leads to excision of more radioactive nodes and can determine the residual radioactivity after excision. The use of a radioactive source as a pointer enables efficient identification of nodes in difficult locations (paraaortic nodes) and in patients with a high body mass index.
Authors: Andrea Gonzalez-Montoro; Cesar David Vera-Donoso; Georgios Konstantinou; Pablo Sopena; Manolo Martinez; Juan Bautista Ortiz; Montserrat Carles; Jose Maria Benlloch; Antonio Javier Gonzalez Journal: Med Phys Date: 2022-05-20 Impact factor: 4.506
Authors: Gijs Hendrik KleinJan; Tessa Buckle; Danny Michel van Willigen; Matthias Nathanaël van Oosterom; Silvia Johara Spa; Harmen Egbert Kloosterboer; Fijs Willem Bernhard van Leeuwen Journal: Molecules Date: 2014-07-08 Impact factor: 4.411