Literature DB >> 21497752

Removing the brakes on cell identity.

Ildem Akerman1, Joris van Arensbergen, Jorge Ferrer.   

Abstract

In this issue of Developmental Cell, Dhawan et al. (2011) show that deletion of the Dnmt1 DNA methyltransferase gene in pancreatic insulin-producing cells makes these cells convert into glucagon-producing cells. This suggests that manipulation of a general epigenetic mechanism may be used to redirect cell fates.
Copyright © 2011 Elsevier Inc. All rights reserved.

Entities:  

Year:  2011        PMID： 21497752     DOI： 10.1016/j.devcel.2011.04.002

Source DB:  PubMed          Journal:  Dev Cell        ISSN： 1534-5807            Impact factor:   12.270


  4 in total

Review 1.  Translational implications of the β-cell epigenome in diabetes mellitus.

Authors:  Justin S Johnson; Carmella Evans-Molina
Journal:  Transl Res       Date:  2014-03-12       Impact factor: 7.012

2.  Novel markers of gonadectomy-induced adrenocortical neoplasia in the mouse and ferret.

Authors:  Maximiliaan Schillebeeckx; Marjut Pihlajoki; Elisabeth Gretzinger; Wei Yang; Franziska Thol; Theresa Hiller; Ann-Kathrin Löbs; Theresa Röhrig; Anja Schrade; Rebecca Cochran; Patrick Y Jay; Markku Heikinheimo; Robi D Mitra; David B Wilson
Journal:  Mol Cell Endocrinol       Date:  2014-10-05       Impact factor: 4.102

3.  A novel dual-color reporter for identifying insulin-producing beta-cells and classifying heterogeneity of insulinoma cell lines.

Authors:  Nan Sook Lee; Joyce G Rohan; Madison Zitting; Sonia Kamath; Andrew Weitz; Arnold Sipos; Paul M Salvaterra; Kouichi Hasegawa; Martin Pera; Robert H Chow
Journal:  PLoS One       Date:  2012-04-18       Impact factor: 3.240

4.  Laser capture microdissection-reduced representation bisulfite sequencing (LCM-RRBS) maps changes in DNA methylation associated with gonadectomy-induced adrenocortical neoplasia in the mouse.

Authors:  Maximiliaan Schillebeeckx; Anja Schrade; Ann-Kathrin Löbs; Marjut Pihlajoki; David B Wilson; Robi D Mitra
Journal:  Nucleic Acids Res       Date:  2013-04-15       Impact factor: 16.971
  4 in total

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