| Literature DB >> 2149722 |
K S Zhao1, C Mancini, G Doria.
Abstract
Astragalus membranaceus extracts injected into normal mice or mice immunodepressed by cyclophosphamide or radiation treatment or by aging are able to enhance the antibody response to a T-dependent antigen. Optimal conditions for maximum effect have been established in normal C3H/HeJ and (C57B1/10 x DBA/2)F1 mice. Enhancement of the antibody response was associated with increase of Th cell activity in normal and immunodepressed mice. The biological activity of endotoxin-free extracts is dependent on the carbohydrate content.Entities:
Mesh:
Substances:
Year: 1990 PMID: 2149722 DOI: 10.1016/0162-3109(90)90038-g
Source DB: PubMed Journal: Immunopharmacology ISSN: 0162-3109