Literature DB >> 21497201

The emerging role of APC/CCdh1 in development.

Dong Hu1, Xinxian Qiao, George Wu, Yong Wan.   

Abstract

The function of APC/C (anaphase-promoting complex/cyclosome) was initially implicated with the onset of anaphase during mitosis, where its association with Cdc20 targets securin for destruction, thereby allowing the separation of two duplicated daughter genomes. When combined with Cdh1, APC regulates G1/S transition and DNA replication during cell cycle. Beyond cell cycle control, results from recent biochemical and mouse genetic studies have attracted our attention to the unexpected impact of APC/C(Cdh1) in cellular differentiation, genomic integrity and pathogenesis of various diseases. This review will aim to summarize current understanding of APC/C(Cdh1) in regulating crucial events during development.
Copyright © 2011 Elsevier Ltd. All rights reserved.

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Year:  2011        PMID： 21497201      PMCID： PMC3982218          DOI： 10.1016/j.semcdb.2011.03.012

Source DB:  PubMed          Journal:  Semin Cell Dev Biol        ISSN： 1084-9521            Impact factor:   7.727


  81 in total

1.  TGFbeta-Smad2 signaling regulates the Cdh1-APC/SnoN pathway of axonal morphogenesis.

Authors:  Judith Stegmüller; Mai Anh Huynh; Zengqiang Yuan; Yoshiyuki Konishi; Azad Bonni
Journal:  J Neurosci       Date:  2008-02-20       Impact factor: 6.167

2.  Balance between Id and E proteins regulates myeloid-versus-lymphoid lineage decisions.

Authors:  Shawn W Cochrane; Ying Zhao; Robert S Welner; Xiao-Hong Sun
Journal:  Blood       Date:  2008-10-16       Impact factor: 22.113

3.  Degradation of Id2 by the anaphase-promoting complex couples cell cycle exit and axonal growth.

Authors:  Anna Lasorella; Judith Stegmüller; Daniele Guardavaccaro; Guangchao Liu; Maria S Carro; Gerson Rothschild; Luis de la Torre-Ubieta; Michele Pagano; Azad Bonni; Antonio Iavarone
Journal:  Nature       Date:  2006-06-28       Impact factor: 49.962

4.  BubR1 is a spindle assembly checkpoint protein regulating meiotic cell cycle progression of mouse oocyte.

Authors:  Liang Wei; Xing-Wei Liang; Qing-Hua Zhang; Mo Li; Ju Yuan; Sen Li; Shao-Chen Sun; Ying-Chun Ouyang; Heide Schatten; Qing-Yuan Sun
Journal:  Cell Cycle       Date:  2010-03-15       Impact factor: 4.534

5.  Nuclear translocation of Skp2 facilitates its destruction in response to TGFβ signaling.

Authors:  Dong Hu; Weijun Liu; George Wu; Yong Wan
Journal:  Cell Cycle       Date:  2011-01-15       Impact factor: 4.534

6.  UBE2S drives elongation of K11-linked ubiquitin chains by the anaphase-promoting complex.

Authors:  Tao Wu; Yifat Merbl; Ying Huo; Jennifer L Gallop; Amit Tzur; Marc W Kirschner
Journal:  Proc Natl Acad Sci U S A       Date:  2010-01-06       Impact factor: 11.205

7.  Destroy to create: E3 ubiquitin ligases in neurogenesis.

Authors:  Judith Stegmüller; Azad Bonni
Journal:  F1000 Biol Rep       Date:  2010-05-24

8.  Securin regulates entry into M-phase by modulating the stability of cyclin B.

Authors:  Petros Marangos; John Carroll
Journal:  Nat Cell Biol       Date:  2008-03-23       Impact factor: 28.824

Review 9.  The spindle-assembly checkpoint in space and time.

Authors:  Andrea Musacchio; Edward D Salmon
Journal:  Nat Rev Mol Cell Biol       Date:  2007-04-11       Impact factor: 94.444

10.  Structures of APC/C(Cdh1) with substrates identify Cdh1 and Apc10 as the D-box co-receptor.

Authors:  Paula C A da Fonseca; Eric H Kong; Ziguo Zhang; Anne Schreiber; Mark A Williams; Edward P Morris; David Barford
Journal:  Nature       Date:  2010-11-24       Impact factor: 49.962
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  12 in total

Review 1.  Functional characterization of Anaphase Promoting Complex/Cyclosome (APC/C) E3 ubiquitin ligases in tumorigenesis.

Authors:  Jinfang Zhang; Lixin Wan; Xiangpeng Dai; Yi Sun; Wenyi Wei
Journal:  Biochim Biophys Acta       Date:  2014-02-22

2.  The anaphase promoting complex promotes NHEJ repair through stabilizing Ku80 at DNA damage sites.

Authors:  Chengxian Ma; Kyungsoo Ha; Min-Su Kim; Young-Woock Noh; Han Lin; Lichun Tang; Qing Zhu; Dan Zhang; Huan Chen; Suxia Han; Pumin Zhang
Journal:  Cell Cycle       Date:  2018-07-18       Impact factor: 4.534

3.  APC/CCdh1 regulates the balance between maintenance and differentiation of hematopoietic stem and progenitor cells.

Authors:  Daniel Ewerth; Stefanie Kreutmair; Andrea Schmidts; Gabriele Ihorst; Marie Follo; Dagmar Wider; Julia Felthaus; Julia Schüler; Justus Duyster; Anna Lena Illert; Monika Engelhardt; Ralph Wäsch
Journal:  Cell Mol Life Sci       Date:  2018-10-24       Impact factor: 9.261

Review 4.  Targeting Cdc20 as a novel cancer therapeutic strategy.

Authors:  Lixia Wang; Jinfang Zhang; Lixin Wan; Xiuxia Zhou; Zhiwei Wang; Wenyi Wei
Journal:  Pharmacol Ther       Date:  2015-04-04       Impact factor: 12.310

5.  CDK4/6 inhibitors downregulate the ubiquitin-conjugating enzymes UBE2C/S/T involved in the ubiquitin-proteasome pathway in ER + breast cancer.

Authors:  Chih-Yi Lin; Chung-Jen Yu; Chun-Yu Liu; Ta-Chung Chao; Chi-Cheng Huang; Ling-Ming Tseng; Jiun-I Lai
Journal:  Clin Transl Oncol       Date:  2022-08-02       Impact factor: 3.340

6.  The E3 ligase APC/C-Cdh1 regulates MEF2A-dependent transcription by targeting SUMO-specific protease 2 for ubiquitination and degradation.

Authors:  Han Lu; Bin Liu; Fu-Jun Zhang; Jin Zhang; Rong Dong; Lei Chen; Dong-Mei Qu; Yan Lu; Bu-Wei Yu
Journal:  Cell Cycle       Date:  2014       Impact factor: 4.534

7.  Cdh1 regulates craniofacial development via APC-dependent ubiquitination and activation of Goosecoid.

Authors:  Rui Shao; Jia Liu; Guang Yan; Jinfang Zhang; Yujiao Han; Jianfeng Guo; Zhan Xu; Zhu Yuan; Jiankang Liu; Marcos Malumbres; Lixin Wan; Wenyi Wei; Weiguo Zou
Journal:  Cell Res       Date:  2016-04-29       Impact factor: 25.617

8.  Polycomb repressive complex PRC2 regulates Xenopus retina development downstream of Wnt/β-catenin signaling.

Authors:  Issam Aldiri; Kathryn B Moore; David A Hutcheson; Jianmin Zhang; Monica L Vetter
Journal:  Development       Date:  2013-06-05       Impact factor: 6.868

9.  Rice APC/C(TE) controls tillering by mediating the degradation of MONOCULM 1.

Authors:  Qibing Lin; Dan Wang; Hui Dong; Suhai Gu; Zhijun Cheng; Jie Gong; Ruizhen Qin; Ling Jiang; Gang Li; Jiu Lin Wang; Fuqing Wu; Xiuping Guo; Xin Zhang; Cailin Lei; Haiyang Wang; Jianmin Wan
Journal:  Nat Commun       Date:  2012-03-20       Impact factor: 14.919

10.  KIF7 Controls the Proliferation of Cells of the Respiratory Airway through Distinct Microtubule Dependent Mechanisms.

Authors:  Garry L Coles; Laurel A Baglia; Kate G Ackerman
Journal:  PLoS Genet       Date:  2015-10-06       Impact factor: 5.917
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