Literature DB >> 21497042

Evaluation of the Xpert™ MRSA/SA Blood Culture assay for the detection of Staphylococcus aureus including strains with reduced vancomycin susceptibility from blood culture specimens.

Peter G Kelley1, Elizabeth A Grabsch, Jenny Farrell, Shirley Xie, Janet Montgomery, Barrie Mayall, Benjamin P Howden.   

Abstract

The Xpert MRSA/SA Blood Culture (BC) assay (Cepheid, Sunnyvale, CA) was prospectively compared to culture and found to have excellent specificity for both Staphylococcus aureus and methicillin-resistant S. aureus (MRSA) in BC specimens with a sensitivity of 75% (3/4) and 100% (17/17), respectively. Among 28 heterogeneous vancomycin-intermediate S. aureus (hVISA)/VISA spiked BCs, the assay correctly identified 84.6% VISA and 80% hVISA isolates as MRSA.
Copyright © 2011 Elsevier Inc. All rights reserved.

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Year:  2011        PMID： 21497042     DOI： 10.1016/j.diagmicrobio.2011.02.006

Source DB:  PubMed          Journal:  Diagn Microbiol Infect Dis        ISSN： 0732-8893            Impact factor:   2.803


  8 in total

1.  Impact of results of a rapid Staphylococcus aureus diagnostic test on prescribing of antibiotics for patients with clustered gram-positive cocci in blood cultures.

Authors:  Jane Davies; Claire L Gordon; Steven Y C Tong; Robert W Baird; Joshua S Davis
Journal:  J Clin Microbiol       Date:  2012-04-04       Impact factor: 5.948

2.  Evaluation of the BinaxNOW Staphylococcus aureus test for rapid identification of Gram-positive cocci from VersaTREK blood culture bottles.

Authors:  Neelam Dhiman; Tamara L Trienski; Linda P DiPersio; Joseph R DiPersio
Journal:  J Clin Microbiol       Date:  2013-06-26       Impact factor: 5.948

3.  Molecular diagnosis of sepsis: New aspects and recent developments.

Authors:  O Liesenfeld; L Lehman; K-P Hunfeld; G Kost
Journal:  Eur J Microbiol Immunol (Bp)       Date:  2014-03-14

4.  Rapid Detection of Methicillin-Resistant Staphylococcus aureus and Methicillin-Susceptible S. aureus Directly from Positive Blood Cultures by Use of the BD Max StaphSR Assay.

Authors:  Justin A Ellem; Tom Olma; Matthew V N O'Sullivan
Journal:  J Clin Microbiol       Date:  2015-12       Impact factor: 5.948

5.  Can the Xpert MRSA/SA BC assay be used as an antimicrobial stewardship tool? A prospective assay validation and descriptive impact assessment study in a South African setting.

Authors:  Kessendri Reddy; Andrew Whitelaw
Journal:  BMC Infect Dis       Date:  2021-02-15       Impact factor: 3.090

Review 6.  AuNPs for identification of molecular signatures of resistance.

Authors:  Bruno Veigas; Alexandra R Fernandes; Pedro V Baptista
Journal:  Front Microbiol       Date:  2014-08-28       Impact factor: 5.640

7.  PCR-based Approaches for the Detection of Clinical Methicillin-resistant Staphylococcus aureus.

Authors:  Ying Liu; Jiang Zhang; Yinduo Ji
Journal:  Open Microbiol J       Date:  2016-04-14

Review 8.  Impact of MRSA on the Military Medical Service and Diagnostic Point-of-Care Options for the Field Setting.

Authors:  Hagen Frickmann
Journal:  Eur J Microbiol Immunol (Bp)       Date:  2018-06-20
  8 in total

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