Literature DB >> 21496368

Comparison of a novel lycra endotracheal tube cuff to standard polyvinyl chloride cuff and polyurethane cuff for fluid leak prevention.

Theodor Kolobow1, Massimo Cressoni, Myra Epp, Ivan Corti, Paolo Cadringher, Alberto Zanella.   

Abstract

BACKGROUND: A high-volume low-pressure endotracheal tube (ETT) cuff forms folds along its contact with the trachea, allowing mucus leakage into the lungs. We developed a thin-walled ETT cuff made of Lycra polyurethane.
METHODS: In vitro, we tested 6 of each of the new prototype Lycra cuff, the Mallinkrodt Hi-Lo ETT (polyvinyl chloride cuff), and the Kimberly-Clark Microcuff ETT (polyurethane cuff), for leakage, in an acrylic mock trachea (inner diameter 20-mm), with a cuff inflation pressure of 20 cm H(2)O. We poured 15 mL of methylene-blue colored water into the acrylic tube above the cuff and observed for leakage for 24 hours.
RESULTS: The Lycra cuffs had no folds upon inflation in the mock trachea and completely prevented fluid leakage for 24 hours (P < .001 vs the Hi-Lo and the Microcuff). The average leakage past the Hi-Lo was 1,182 ± 1,321 mL/h. The average leakage past the Microcuff was 1.2 ± 0.4 mL/h (P < .001 vs the Hi-Lo).
CONCLUSIONS: Our Lycra cuff provided complete tracheal sealing in vitro.

Entities:  

Mesh:

Substances:

Year:  2011        PMID: 21496368     DOI: 10.4187/respcare.01099

Source DB:  PubMed          Journal:  Respir Care        ISSN: 0020-1324            Impact factor:   2.258


  7 in total

1.  Beware the siren's song of novel endotracheal tube designs.

Authors:  Michael Klompas; Lorenzo Berra; Richard Branson
Journal:  Intensive Care Med       Date:  2017-03-31       Impact factor: 17.440

Review 2.  Novel preventive strategies for ventilator-associated pneumonia.

Authors:  Andrea Coppadoro; Edward Bittner; Lorenzo Berra
Journal:  Crit Care       Date:  2012-12-12       Impact factor: 9.097

3.  Pathogenic Link Between Postextubation Pneumonia and Ventilator-Associated Pneumonia: An Experimental Study.

Authors:  Emanuele Rezoagli; Alberto Zanella; Massimo Cressoni; Lorenzo De Marchi; Theodor Kolobow; Lorenzo Berra
Journal:  Anesth Analg       Date:  2017-04       Impact factor: 5.108

4.  Prevention of Lung Bacterial Colonization With a Leak-Proof Endotracheal Tube Cuff: An Experimental Animal Study.

Authors:  Emanuele Rezoagli; Massimo Cressoni; Giacomo Bellani; Giacomo Grasselli; Antonio M Pesenti; Theodor Kolobow; Alberto Zanella
Journal:  Respir Care       Date:  2019-04-23       Impact factor: 2.258

5.  Comparison of polyurethane tracheal tube cuffs and conventional polyvinyl chloride tube cuff for prevention of ventilator-associated pneumonia: A systematic review with meta-analysis.

Authors:  Minami Saito; Koichi Maruyama; Takahiro Mihara; Hiroshi Hoshijima; Go Hirabayashi; Tomio Andoh
Journal:  Medicine (Baltimore)       Date:  2021-03-05       Impact factor: 1.817

6.  Insights on the role of antimicrobial cuffed endotracheal tubes in preventing transtracheal transmission of VAP pathogens from an in vitro model of microaspiration and microbial proliferation.

Authors:  Joel Rosenblatt; Ruth Reitzel; Ying Jiang; Ray Hachem; Issam Raad
Journal:  Biomed Res Int       Date:  2014-04-10       Impact factor: 3.411

Review 7.  The value of polyurethane-cuffed endotracheal tubes to reduce microaspiration and intubation-related pneumonia: a systematic review of laboratory and clinical studies.

Authors:  Stijn I Blot; Jordi Rello; Despoina Koulenti
Journal:  Crit Care       Date:  2016-06-24       Impact factor: 9.097

  7 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.