| Literature DB >> 21495879 |
Talgar Shaymurat1, Jianxiu Gu, Changshan Xu, Zhikun Yang, Qing Zhao, Yuxue Liu, Yichun Liu.
Abstract
The effects of zinc oxide nanoparticles (ZnO NPs) on the root growth, root apical meristem mitosis and mitotic aberrations of garlic (Allium sativum L.) were investigated. ZnO NPs caused a concentration-dependent inhibition of root length. When treated with 50 mg/L ZnO NPs for 24 h, the root growth of garlic was completely blocked. The 50% inhibitory concentration (IC(50)) was estimated to be 15 mg/L. The mitosis index was also decreased in a concentration- and time-dependent manner. ZnO NPs also induced several kinds of mitotic aberrations, mainly consisted of chromosome stickiness, bridges, breakages and laggings. The total percentage of abnormal cells increased with the increase of ZnO NPs concentration and the prolongation of treatment time. The investigation provided new information for the possible genotoxic effects of ZnO NPs on plants.Entities:
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Year: 2011 PMID： 21495879 DOI： 10.3109/17435390.2011.570462
Source DB: PubMed Journal: Nanotoxicology ISSN： 1743-5390 Impact factor: 5.913