Literature DB >> 21495659

Triazole and dihydroimidazole alkaloids from the marine sediment-derived fungus Penicillium paneum SD-44.

Chun-Shun Li1, Chun-Yan An, Xiao-Ming Li, Shu-Shan Gao, Chuan-Ming Cui, Hao-Fen Sun, Bin-Gui Wang.   

Abstract

A novel triazole carboxylic acid, penipanoid A (1), two new quinazolinone alkaloids, penipanoids B (2) and C (3), and a very recently reported quinazolinone derivative (4) were isolated from the marine sediment-derived fungus Penicillium paneum SD-44. Their structures were elucidated by spectroscopic analysis, and the structure for 1 was confirmed by X-ray crystallographic analysis. Compound 1 represents the first example of a triazole derivative from marine sediment-derived fungi, and compound 2 is a rare quinazolinone derivative having a dihydroimidazole ring system. The cytotoxicity of compounds 1 and 4 and the antimicrobial activity of 1-4 were evaluated.

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Year:  2011        PMID： 21495659     DOI： 10.1021/np200037z

Source DB:  PubMed          Journal:  J Nat Prod        ISSN： 0163-3864            Impact factor:   4.050


  12 in total

1.  Classification of Aspergillus, Penicillium, Talaromyces and related genera (Eurotiales): An overview of families, genera, subgenera, sections, series and species.

Authors:  J Houbraken; S Kocsubé; C M Visagie; N Yilmaz; X-C Wang; M Meijer; B Kraak; V Hubka; K Bensch; R A Samson; J C Frisvad
Journal:  Stud Mycol       Date:  2020-06-27       Impact factor: 16.097

Review 2.  Comprehensive Overview on the Chemistry and Biological Activities of Selected Alkaloid Producing Marine-Derived Fungi as a Valuable Reservoir of Drug Entities.

Authors:  Fadia S Youssef; Jesus Simal-Gandara
Journal:  Biomedicines       Date:  2021-04-28

3.  Secondary metabolites from Penicillium pinophilum SD-272, a marine sediment-derived fungus.

Authors:  Ming-Hui Wang; Xiao-Ming Li; Chun-Shun Li; Nai-Yun Ji; Bin-Gui Wang
Journal:  Mar Drugs       Date:  2013-06-21       Impact factor: 5.118

4.  Aniquinazolines A-D, four new quinazolinone alkaloids from marine-derived endophytic fungus Aspergillus nidulans.

Authors:  Chun-Yan An; Xiao-Ming Li; Chun-Shun Li; Ming-Hui Wang; Gang-Ming Xu; Bin-Gui Wang
Journal:  Mar Drugs       Date:  2013-07-23       Impact factor: 5.118

Review 5.  Bioactive Compounds Produced by Strains of Penicillium and Talaromyces of Marine Origin.

Authors:  Rosario Nicoletti; Antonio Trincone
Journal:  Mar Drugs       Date:  2016-02-18       Impact factor: 5.118

Review 6.  Exploring Structural Diversity of Microbe Secondary Metabolites Using OSMAC Strategy: A Literature Review.

Authors:  Rui Pan; Xuelian Bai; Jianwei Chen; Huawei Zhang; Hong Wang
Journal:  Front Microbiol       Date:  2019-02-26       Impact factor: 5.640

7.  Nitroalkanes as electrophiles: synthesis of triazole-fused heterocycles with neuroblastoma differentiation activity.

Authors:  Nicolai A Aksenov; Alexander V Aksenov; Nikita K Kirilov; Nikolai A Arutiunov; Dmitrii A Aksenov; Vladimir Maslivetc; Zhenze Zhao; Liqin Du; Michael Rubin; Alexander Kornienko
Journal:  Org Biomol Chem       Date:  2020-08-19       Impact factor: 3.876

8.  Cytotoxic anthranilic acid derivatives from deep sea sediment-derived fungus Penicillium paneum SD-44.

Authors:  Chun-Shun Li; Xiao-Ming Li; Shu-Shan Gao; Yan-Hua Lu; Bin-Gui Wang
Journal:  Mar Drugs       Date:  2013-08-21       Impact factor: 5.118

Review 9.  Marine-Derived Penicillium Species as Producers of Cytotoxic Metabolites.

Authors:  Sen Liu; Mingzhi Su; Shao-Jiang Song; Jee H Jung
Journal:  Mar Drugs       Date:  2017-10-24       Impact factor: 5.118

10.  New Isoxazolidine-Conjugates of Quinazolinones-Synthesis, Antiviral and Cytostatic Activity.

Authors:  Dorota G Piotrowska; Graciela Andrei; Dominique Schols; Robert Snoeck; Magdalena Grabkowska-Drużyc
Journal:  Molecules       Date:  2016-07-22       Impact factor: 4.411
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