| Literature DB >> 21494950 |
Petri M Pihko1, Inkeri Majander, Anniina Erkkilä.
Abstract
The reversible reaction of primary or secondary amines with enolizable aldehydes or ketones affords nucleophilic intermediates, enamines. With chiral amines, catalytic enantioselective reactions via enamine intermediates become possible. In this review, structure-activity relationships and the scope as well as current limitations of enamine catalysis are discussed.Entities:
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Year: 2010 PMID： 21494950 DOI： 10.1007/978-3-642-02815-1_21
Source DB: PubMed Journal: Top Curr Chem ISSN： 0340-1022