BACKGROUND: Using antiretroviral therapies for HIV prevention relies on patient adherence and avoidance of co-occurring sexually transmitted infections. PURPOSE: The objective of this study is to simultaneously examine HIV treatment adherence and sexual risks for HIV transmission. METHODS: This study is a prospective cohort of 201 men and 55 women diagnosed with HIV/AIDS infection. RESULTS: A total of 32% men and 39% women engaged in unprotected intercourse with at least one HIV negative or unknown HIV status sex partner over 12 months. Nearly half (46%) of participants with HIV negative or unknown HIV status unprotected sex partners had detectable HIV viral load and were significantly more likely to have contracted a sexually transmitted infection since their HIV diagnosis. Individuals at higher risk for transmitting HIV were also less adherent to antiretroviral therapies. CONCLUSIONS: Programs that aim to use antiretroviral therapies for HIV prevention require careful attention to adherence, sexually transmitted co-infections, and substance use.
BACKGROUND: Using antiretroviral therapies for HIV prevention relies on patient adherence and avoidance of co-occurring sexually transmitted infections. PURPOSE: The objective of this study is to simultaneously examine HIV treatment adherence and sexual risks for HIV transmission. METHODS: This study is a prospective cohort of 201 men and 55 women diagnosed with HIV/AIDS infection. RESULTS: A total of 32% men and 39% women engaged in unprotected intercourse with at least one HIV negative or unknown HIV status sex partner over 12 months. Nearly half (46%) of participants with HIV negative or unknown HIV status unprotected sex partners had detectable HIV viral load and were significantly more likely to have contracted a sexually transmitted infection since their HIV diagnosis. Individuals at higher risk for transmitting HIV were also less adherent to antiretroviral therapies. CONCLUSIONS: Programs that aim to use antiretroviral therapies for HIV prevention require careful attention to adherence, sexually transmitted co-infections, and substance use.
Authors: K Rivet Amico; William Barta; Deborah J Konkle-Parker; Jeffrey D Fisher; Deborah H Cornman; Paul A Shuper; William A Fisher Journal: AIDS Behav Date: 2007-09-18
Authors: Moupali Das; Priscilla Lee Chu; Glenn-Milo Santos; Susan Scheer; Eric Vittinghoff; Willi McFarland; Grant N Colfax Journal: PLoS One Date: 2010-06-10 Impact factor: 3.240
Authors: Jill Blumenthal; Richard Haubrich; Sonia Jain; Xiaoying Sun; Michael Dube; Eric Daar; Joel Milam; Sheldon Morris Journal: Int J STD AIDS Date: 2014-01-22 Impact factor: 1.359
Authors: Dean G Cruess; Kaylee E Burnham; David J Finitsis; Brett M Goshe; Lauren Strainge; Moira Kalichman; Tamar Grebler; Chauncey Cherry; Seth C Kalichman Journal: Ann Behav Med Date: 2018-02-05
Authors: Robert H Remien; Curtis Dolezal; Glenn J Wagner; Kathy Goggin; Ira B Wilson; Robert Gross; Marc I Rosen; Jie Shen; Jane M Simoni; Carol E Golin; Julia H Arnsten; David R Bangsberg; Honghu Liu Journal: AIDS Behav Date: 2014-08
Authors: Panagiotis Vagenas; Marwan M Azar; Michael M Copenhaver; Sandra A Springer; Patricia E Molina; Frederick L Altice Journal: Curr HIV/AIDS Rep Date: 2015-12 Impact factor: 5.071