Literature DB >> 21493210

Cost burden of chronic rhinosinusitis: a claims-based study.

Neil Bhattacharyya1, Richard R Orlandi, Jeff Grebner, Melissa Martinson.   

Abstract

OBJECTIVE: To quantify the cost burden and utilization of health care for chronic rhinosinusitis (CRS). STUDY
DESIGN: Historical cohort study.
SETTING: Academic medical centers.
METHODS: Medical claims data from 2003 to 2008 were analyzed. Patients were defined as having chronic sinus disease if they had a minimum of 2 CRS-related diagnoses with either computed tomography scanning or endoscopy performed between diagnoses. The prevalence and costs of CRS from the payer perspective (reimbursements) were determined.
RESULTS: More than 4.4 million patients with an average of 3.1 years of eligibility and at least 1 diagnosis of acute rhinosinusitis (ARS) or CRS were studied. A total of 5.5% (95% confidence interval [CI], 5.4%-5.6%) of those with ARS were diagnosed with CRS in the subsequent 4 years. Among patients with chronic disease, after 12 months, 39% were still consuming care for CRS, and after 24 months, nearly 28% were still doing so. Of the CRS patients whose diagnosis was confirmed with endoscopy or radiology, 46.2% underwent endoscopic sinus surgery (ESS). In the year prior to ESS, patient care costs averaged $2449 ($2341-$2556). The ESS procedure plus 45-day postprocedure debridement and medical therapy costs averaged $7726 ($7554-$7898). In the year following the 45-day postprocedure period, consumption dropped by $885 (P < .0001). In the second year following ESS, therapy costs dropped an additional $446 (P < .0001).
CONCLUSIONS: A significant proportion of CRS patients require ongoing treatment of their sinus disease for years. Sinus surgery appears to reduce consumption of rhinosinusitis-related health care, but costs related to the procedure are significant.

Entities:  

Mesh:

Year:  2011        PMID: 21493210     DOI: 10.1177/0194599810391852

Source DB:  PubMed          Journal:  Otolaryngol Head Neck Surg        ISSN: 0194-5998            Impact factor:   3.497


  41 in total

Review 1.  Surgical versus medical interventions in CRS and nasal polyps: comparative evidence between medical and surgical efficacy.

Authors:  Osama Dessouky; Claire Hopkins
Journal:  Curr Allergy Asthma Rep       Date:  2015-11       Impact factor: 4.806

Review 2.  Regulation of airway inflammation by Siglec-8 and Siglec-9 sialoglycan ligand expression.

Authors:  Robert P Schleimer; Ronald L Schnaar; Bruce S Bochner
Journal:  Curr Opin Allergy Clin Immunol       Date:  2016-02

Review 3.  Comprehensive review on endonasal endoscopic sinus surgery.

Authors:  Rainer K Weber; Werner Hosemann
Journal:  GMS Curr Top Otorhinolaryngol Head Neck Surg       Date:  2015-12-22

4.  The personal financial burden of chronic rhinosinusitis: A Canadian perspective.

Authors:  Jonathan Yip; Allan D Vescan; Ian J Witterick; Eric Monteiro
Journal:  Am J Rhinol Allergy       Date:  2017-07-01       Impact factor: 2.467

5.  Cytokines in Chronic Rhinosinusitis. Role in Eosinophilia and Aspirin-exacerbated Respiratory Disease.

Authors:  Whitney W Stevens; Christopher J Ocampo; Sergejs Berdnikovs; Masafumi Sakashita; Mahboobeh Mahdavinia; Lydia Suh; Tetsuji Takabayashi; James E Norton; Kathryn E Hulse; David B Conley; Rakesh K Chandra; Bruce K Tan; Anju T Peters; Leslie C Grammer; Atsushi Kato; Kathleen E Harris; Roderick G Carter; Shigeharu Fujieda; Robert C Kern; Robert P Schleimer
Journal:  Am J Respir Crit Care Med       Date:  2015-09-15       Impact factor: 21.405

Review 6.  Long-term successes of various sinus surgeries: a comprehensive analysis.

Authors:  Gregg H Goldstein; David W Kennedy
Journal:  Curr Allergy Asthma Rep       Date:  2013-04       Impact factor: 4.806

7.  Searching for distinct mechanisms in eosinophilic and noneosinophilic airway inflammation.

Authors:  Atsushi Kato; Kathryn E Hulse
Journal:  Am J Respir Crit Care Med       Date:  2014-09-15       Impact factor: 21.405

8.  Proprotein convertases generate a highly functional heterodimeric form of thymic stromal lymphopoietin in humans.

Authors:  Julie A Poposki; Aiko I Klingler; Whitney W Stevens; Anju T Peters; Kathryn E Hulse; Leslie C Grammer; Robert P Schleimer; Kevin C Welch; Stephanie S Smith; Douglas M Sidle; David B Conley; Bruce K Tan; Robert C Kern; Atsushi Kato
Journal:  J Allergy Clin Immunol       Date:  2016-10-12       Impact factor: 10.793

Review 9.  Pathogenesis of nasal polyposis.

Authors:  K E Hulse; W W Stevens; B K Tan; R P Schleimer
Journal:  Clin Exp Allergy       Date:  2015-02       Impact factor: 5.018

10.  Solitary chemosensory cells producing interleukin-25 and group-2 innate lymphoid cells are enriched in chronic rhinosinusitis with nasal polyps.

Authors:  Neil N Patel; Michael A Kohanski; Ivy W Maina; Vasiliki Triantafillou; Alan D Workman; Charles C L Tong; Edward C Kuan; John V Bosso; Nithin D Adappa; James N Palmer; De'Broski R Herbert; Noam A Cohen
Journal:  Int Forum Allergy Rhinol       Date:  2018-05-09       Impact factor: 3.858

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