| Literature DB >> 21493064 |
Liping Wang1, James A Hubert, Susan J Lee, Jie Pan, Su Qian, Marc L Reitman, Alison M Strack, Drew T Weingarth, Douglas J MacNeil, Ann E Weber, Scott D Edmondson.
Abstract
A series of six-membered heterocycle carboxamides were synthesized and evaluated as cholecystokinin 1 receptor (CCK1R) agonists. A pyrimidine core proved to be the best heterocycle, and SAR studies resulted in the discovery of analog 5, a potent and structurally diverse CCK1R agonist.Entities:
Mesh：
Substances：
Year: 2011 PMID： 21493064 DOI： 10.1016/j.bmcl.2011.03.069
Source DB: PubMed Journal: Bioorg Med Chem Lett ISSN： 0960-894X Impact factor: 2.823