Literature DB >> 21492604

Primary meningeal T-cell lymphoma at the clivus mimicking a meningioma.

Stefan Grau1, Ulrich Schueller, Carolin Weiss, Jörg-Christian Tonn.   

Abstract

BACKGROUND: Most primary lymphomas of the central nervous system (CNS) are of B-cell origin and are found intra-axially, with a few reported cases of skull base tumors involving the upper clivus or sellar region or both. In this case, a tumor resembling a clivus meningioma without osseous involvement was surgically removed and turned out to be a primary T-cell lymphoma. CASE REPORT: A 60-year-old woman presented with slight right-sided abducens nerve palsy. Cranial imaging revealed an extra-axial mass at the caudal clivus resembling a meningioma. The tumor was removed surgically; smear preparations obtained intraoperatively were inconclusive presumably because of preoperative steroid treatment. The final diagnosis was peripheral T-cell lymphoma, not otherwise unspecified. The patient developed a secondary meningiosis supposedly caused by surgery.
CONCLUSIONS: Although a very rare entity among primary T-cell lymphomas of the CNS, these tumors also can occur as skull base lesions without involvement of the bone. Preoperative steroid medication may complicate intraoperative histologic assessment and lead to inadequate treatment of these tumors.
Copyright © 2010 Elsevier Inc. All rights reserved.

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Year:  2011        PMID: 21492604     DOI: 10.1016/j.wneu.2010.06.020

Source DB:  PubMed          Journal:  World Neurosurg        ISSN: 1878-8750            Impact factor:   2.104


  3 in total

1.  Primary non-hodgkin lymphoma of lateral skull base mimicking a trigeminal schwannoma: case report.

Authors:  Liu Yang; Wen Li; Min Chen
Journal:  Int J Clin Exp Med       Date:  2015-06-15

Review 2.  The identification of H3F3A mutation in giant cell tumour of the clivus and the histological diagnostic algorithm of other clival lesions permit the differential diagnosis in this location.

Authors:  Federica Scotto di Carlo; Giuseppina Divisato; Maurizio Iacoangeli; Teresa Esposito; Fernando Gianfrancesco
Journal:  BMC Cancer       Date:  2018-04-02       Impact factor: 4.430

Review 3.  Isolated hypoglossal nerve palsy as a presenting symptom of metastatic peripheral T-cell lymphoma - not otherwise specified (PTCL-NOS): a unique case & a review of the literature.

Authors:  Emily Bryer; David Henry
Journal:  Int J Hematol Oncol       Date:  2018-06-28
  3 in total

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