| Literature DB >> 21491897 |
Yoshiyasu Ichikawa1, Yasunori Matsuda, Ken Okumura, Mitsuhiro Nakamura, Toshiya Masuda, Hiyoshizo Kotsuki, Keiji Nakano.
Abstract
The first nonracemic synthesis of (+)-geranyllinaloisocyanide, starting with (-)-lactic acid methyl ester, has been accomplished by exploiting a [3.3] sigmatropic rearrangement of allyl cyanate. The synthesis enables assignment of the S configuration of the C(3) isocyano substituted, quaternary stereogenic center in natural geranyllinaloisocyanide.Entities:
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Year: 2011 PMID： 21491897 DOI： 10.1021/ol200308m
Source DB: PubMed Journal: Org Lett ISSN： 1523-7052 Impact factor: 6.005